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  • The novel coronavirus has been declared a global health emergency by the World Health Organisation.

  • So how are scientists responding?

  • And what can science do to help control the outbreak?

  • A top priority is epidemiology.

  • Epidemiologists are on the front line, trying to understand how and why the virus is spreading.

  • They gather data on the timing and location of new cases, where new infections are coming from and how long symptoms take to appear.

  • These data go into models that can predict how fast the infection might spread.

  • This is critical for both creating containment plans, and assessing whether counter-measures are actually working.

  • By looking at the patterns of spread, epidemiologists can infer the mode of transmission, such as in saliva or through the air.

  • Epidemiologists also need to know whether people who are infected but not showing symptoms could still pass on the disease, something which would make this coronavirus harder to wipe out.

  • Understanding the source of the virus is also important.

  • The virus likely originated in an animal before jumping to a human host.

  • Genetic analysis of samples taken from the market in Wuhan, where the outbreak started, could tell scientists which animal and help prevent future outbreaks.

  • Understanding how the virus spreads is a vital first step for containing it, but scientists also need to know how the virus itself functions.

  • And that is the job of virologists.

  • Across the world, virologists are scrambling to get their hands on physical samples of the novel coronavirus.

  • This work involves growing the virus in cultured cells and infecting animals in order to study it closely.

  • There's lots to learn.

  • Virologists can measure the survival time of the virus in droplets like those from a cough or a sneeze.

  • Animal models may show how the infection actually gets passed between individuals.

  • And working out the structure of viral proteins and the identity of the receptors they use to enter cells could inform potential treatments.

  • The genome of the virus can also hold clues.

  • Genetic sequences from dozens of patient samples are publicly available and have already been used to develop diagnostic tests.

  • But actual samplesin human cell cultures and animal models - will be needed to test vaccines and drugs.

  • This is where biomedical science comes in.

  • Drug development is a slow process, so researchers are having to work fast to find therapies for this new threat.

  • One of the most powerful tools biomedical scientists could develop is a vaccine, but this is a longer term solution.

  • A more imminent possibility is to inject patients with antibodies against the virus.

  • Finding antibodies that recognise it might not be so difficult, but mass producing enough antibodies, even for trials, could take months.

  • Antiviral drugs are also an option.

  • These are small molecules that interfere with viral replication, but developing them from scratch takes years.

  • So researchers are hoping that drugs already developed to treat things like HIV, could prove effective and trials have already started.

  • If counter-measures fail, coronavirus could become what's called 'endemic', recurring regularly like the flu.

  • That would make it extremely hard to eradicate.

  • Fighting this outbreak will require a range of scientific tools, from genetic sequencing to mathematical modelling.

  • And for all of that, researchers need data.

  • Many publishers and labs have made commitments to make all research free to access, encouraging collaboration and prioritising global health.

  • Time will tell how successful it will be.

The novel coronavirus has been declared a global health emergency by the World Health Organisation.

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B1 中級 美國腔 武漢肺炎 新型冠狀病毒 新冠肺炎 COVID-19

科學家如何對抗冠狀病毒。三分鐘指南 (How scientists are fighting the coronavirus: A three minute guide)

  • 92 2
    Courtney Shih 發佈於 2021 年 01 月 14 日
影片單字

重點單字

extremely

US /ɪk'strimlɪ/

UK /ɪkˈstri:mli/

  • adv. 極端地 ; 非常地
vital

US /'vaɪtl/

UK /'vaɪtl/

  • adj. 至關重要的:有活力的;重要
critical

US /ˈkrɪtɪkəl/

UK /ˈkrɪtɪkl/

  • adj. 危急;關鍵的;批評的
access

US /ˈæksɛs/

UK /'ækses/

  • n. 接近 ; 接近的機會 ; 晤面 ; 捷徑 ; 通路 ; 入口 ; 發作 ; 激發 ; 增加 ; 附加 ; 使用 ; 存取 ; 進接
  • v. 訪問
physical

US /ˈfɪzɪkəl/

UK /ˈfɪzɪkl/

  • n. 身體檢查
  • adj. 物質的 ; 自然的 ; 天然的 ; 自然科學的 ; 物理的 ; 物理學的 ; 身體的 ; 肉體的 ; 物理;物質的
structure

US /ˈstrʌk.tʃɚ/

UK /ˈstrʌk.tʃə/

  • n. 結構;構造;機構;體系
  • v. 構成;組織
effective

US /ɪˈfɛktɪv/

UK /ɪˈfektɪv/

  • adj. 有效的
treat

US /trit/

UK /tri:t/

  • v. 宴請;款待;招待;治療;處理;對待
  • n. 對待 ;;點心, 零嘴
interfere

US /ˌɪntɚˈfɪr/

UK /ˌɪntə'fɪə(r)/

  • v. 妨礙 ; 干擾
develop

US /dɪˈvɛləp/

UK /dɪ'veləp/

  • v. 詳盡闡述;建立;打造;使發達 ; 使發育 ; 展開 ; 詳述 ; 逐漸產生 ; 移有利的位 ; 顯像 ; 發展 ; 顯出 ; 籀;沖洗(底片)

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