Name: 為什麼我們應該給每個人施打 Ozempic？ (Why We Should Give Ozempic to Everybody)
Uploaded: 2026-02-17T21:35:30.000Z
Duration: 12 min 52 s

Ozempic or Mounjaro have done what diets and willpower have failed to do so far.

Ozempic 或 Mounjaro 達成了到目前為止飲食控制和意志力都做不到的事。

Make millions lose massive amounts of weight with seemingly mild side effects.

讓數百萬人大幅減重，而且副作用似乎很輕微。

More than 1 in 8 US adults have tried the drugs.

美國有超過八分之一的成年人試過這些藥物。

For the first time in history, the country's obesity rate actually fell.

歷史上，這個國家的肥胖率首次出現下降。

Since obesity is one of the unhealthiest things in the world, this seriously poses the question, should we give these drugs to everyone who is overweight to spark a medical revolution like we did with antibiotics and vacc?

既然肥胖是世界上最不健康的因素之一，這就嚴肅地引發了一個問題：我們應該把這些藥物給所有體重過重的人，來引發一場像抗生素和疫苗一樣的醫療革命嗎？

At its core, being overweight or obese is a mismatch between how much you eat and how much your body needs.

根本來說，體重過重或肥胖，是你的飲食攝取量和你身體所需量之間的不匹配。

Eat more calories than you burn and your body will store them as fat.

你攝取的熱量超過你燃燒的，你的身體就會將其儲存為脂肪。

But just because something depends on what you do, it doesn't mean it's your fault.

但事情的成敗取決於你的行動，並不代表是你的錯。

Your drive to eat is programmed by evolution and can easily hijack your conscious decisions.

你想吃的慾望是演化決定的，很容易就會影響你理性的判斷。

For most of our history, food was scarce.

在我們歷史的大部分時間裡，食物都是很稀少的。

So when our ancestors found a calorie bomb, binging on it was the best of ide.

所以當我們的祖先找到高熱量的食物時，大吃特吃是最好的策略。

The more sugar, fat and salt, the better.

Our brains are wired to love these foods.

我們的大腦天生就喜歡這些食物。

They bring pleasure, enjoyment, and mental release.

它們帶來愉悅、享受和心靈的釋放。

This helped us survive in a world where food was the most important thing to worry about each day.

這幫助我們在食物是每天最重要擔憂的世界裡生存下來。

And then the world changed overnight and suddenly food was cheap, calorie dense and hyper palatable.

然後世界在一夕之間改變，食物突然變得便宜、高熱量又超級美味。

Our ancient biology hijacked our modern behavior.

我們古老的生理機制劫持了我們現代的行為。

Most of us can't help ourselves and overeat regularly.

大多數人都忍不住，經常吃過量。

Today, over 40% of adults are overweight.

現在，超過四成的成人體重過重。

Obesity affects 1 billion humans and kills almost 4 million annually.

肥胖影響了十億人口，每年造成近四百萬人死亡。

If trends continue, by 2050, 1 in 3 adults on Earth will be obese and half of humanity will be overweight.

如果趨勢持續下去，到2050年，地球上每三個成人中就有一個會肥胖，一半的人口會體重過重。

Since being overweight is also shamed on top of being unhealthy, we tried to fix our overeating behavior with all sorts of, well, behavioral methods.

體重過重不僅不健康，還會被羞辱，所以我們試圖用各種方法來修正我們的過度飲食行為。

The world is filled with diets and healthy habits campaigns.

世界上充滿了各種飲食法和健康習慣的宣導。

But anyone who's been on a diet before knows that it's hard and no fun at all.

但任何有節食經驗的人都知道，這很難，而且一點都不好玩。

Not only are you fighting your deep evolutionary programming, you're cutting down on a major source of comfort, social activity and good feelings.

你不僅在對抗你深層的演化程式，還在削減一個主要的慰藉、社交活動和美好感受的來源。

And if you've finally lost weight and want to ease up a little, you're back in the regular world full of amazing foods.

如果你終於瘦下來，想稍微放鬆一下，你就又回到了充滿美味食物的正常世界。

Self regulating around modern food is just too hard.

在現代食物面前自我約束實在太難了。

So almost everybody who loses weight struggles to keep it that way or puts back on even more.

所以幾乎所有減重成功的人，都難以維持成果，甚至會胖回更多。

So if fixing our habits doesn't work, what if we fix our biology before we get there?

所以如果改變習慣沒用，那我們能不能先從生物學下手呢？

讓我們來修正一些比較簡單的。

First, how we engage with the news every day.

首先，我們每天如何接觸新聞。

Our partner, Ground News, is a website and app built to help you think critically about the information you consume, a mission we fully support.

我們的合作夥伴 Ground News 是一個網站和 App，旨在幫助你批判性地思考你所接收的資訊，這也是我們全力支持的使命。

They curate news articles from across the globe, adding context on political bias, reliability, ownership, and

他們會從全球各地精選新聞文章，並補充政治傾向、可靠性、所有權等相關資訊，

summaries that highlight what each side is leaving out.

還有摘要，重點說明各方遺漏了什麼。

You can even compare headlines to see how bias shapes the narrative.

你甚至可以比較標題，看看偏見如何形塑敘事。

The same weight loss drug story might be framed as a miracle by some outlets, while others warn about harmful trends.

同樣的減重藥物新聞，有些媒體可能描繪成奇蹟，有些則警告有害趨勢。

Ground News also reveals blind spots, stories that only one side is covering, showing you what your usual news feed is hiding.

Ground News 也會揭露盲點，也就是隻有單一方在報導的故事，讓你看到你的新聞動態通常會隱藏什麼。

As information bubbles are becoming the norm, thinking critically about the news is no longer optional, and

隨著資訊泡泡越來越普遍，批判性地思考新聞已經不再是選擇題，而是

Ground News makes it easier to do just that.

Ground News 讓這件事變得更容易。

If you'd like to give them a try, go to ground.newsnutshell or scan the QR code on the screen.

如果你想試試看，可以到 ground.newsnutshell 或掃描螢幕上的 QR code。

Using this Link gives you 40% off an unlimited access subscription and directly supports our channel and now back to Losing weight, Ozempic and Co Many eating behaviors, eat now or later chocolate or vegetables are actually governed by an orchestra of hormones that are not within your control.

使用這個連結，你可以享有無限訂閱 40% 的折扣，同時也能直接支持我們的頻道。現在回到減重話題，Ozempic 和其他藥物。許多飲食行為，像是現在吃還是晚點吃巧克力或蔬菜，其實是由一組你無法控制的荷爾蒙指揮的。

You're not hungry in the evening because you decide to be, or because this is when your body needs energy, but

你晚上不覺得餓，不是因為你決定不餓，也不是因為你的身體在這個時候需要能量，而是

because your body relieves certain hormones.

因為你的身體會釋放某些荷爾蒙。

And it turns out your fat is one of the major regulators of this orchestra.

結果發現，你的脂肪是這個指揮樂團的主要調控者之一。

If you're overweight or obese, the excess fat is throwing your hormonal orchestra out of tune.

如果你過重或肥胖，過多的脂肪會讓你的荷爾蒙指揮樂團失衡。

This may make you more hungry or push you to overeat more, creating insulin resistance that causes type 2 diabetes and so on.

這可能會讓你更餓，或讓你更想吃過量，進而造成胰島素阻抗，導致第二型糖尿病等等。

我們做了一支影片，如果你想知道更多細節，但

there's one specific hormone that plays its tune quietly in the background, even in obese people.

有一個特定的荷爾蒙，即使在肥胖的人身上，也會在背景中悄悄地演奏它的旋律。

Like peptide 1 or GLP1, it's one of the hormones your body releases after a meal.

像是胜肽 1 或 GLP1，它是你身體在一餐後釋放的一種荷爾蒙。

It tells your pancreas to release more insulin to keep blood sugar in check and slows down your digestion to keep food in your stomach and in your brain.

它會告訴你的胰臟釋放更多胰島素來維持血糖穩定，並減緩你的消化速度，讓食物留在胃裡，也留在你的腦袋裡。

It increases your feeling of fullness and being satisfied, curbing your appetite.

它會增加你的飽足感和滿足感，抑制你的食慾。

Once in your bloodstream, GLP1 disappears in barely two minutes, its song quickly fading away.

GLP1 一旦進入血液，不到兩分鐘就消失了，它的旋律很快就消逝。

所以有一天，科學家們想到了一個點子。

What if we made artificial copies of GLP1 that play the same song, but louder and much longer?

如果我們製造出 GLP1 的人造複製品，讓它們唱出同樣的旋律，但更響亮、更持久呢？

A GLP1 signal that stays in your body would boost insulin and silence appetite.

一個留在你體內的 GLP1 訊號，就能促進胰島素分泌，並抑制食慾。

The first artificial GLP1 was approved in 2005 for diabetes and in 2014 for obesity.

第一個人造 GLP1 在 2005 年獲準用於糖尿病，並在 2014 年獲準用於肥胖症。

But the revolution came with semaglutide and Tirzepatide, Ozempic and mounjaro.

但革命性的突破來自於 semaglutide 和 Tirzepatide，也就是 Ozempic 和 Mounjaro。

Really powerful GLP1 agonists that play their songs in your bloodstream for up to a week.

這些強大的 GLP1 促效劑，能在你的血液中持續歌唱長達一週。

They send out a loud and steady signal that dials down your appetite 24 7.

它們會發出響亮且穩定的訊號，全天候抑制你的食慾。

You still enjoy food, but you feel full and satisfied much sooner, making it easy to not overeat.

你仍然能享受美食，但很快就感到飽足和滿足，讓你輕鬆避免過量飲食。

And since the song never really switches off, you feel less hungry throughout your day, making you eat less often.

而且因為這個訊號幾乎不會關閉，你一整天都會覺得比較不餓，讓你吃得比較少。

Hunger is largely genetic, so especially people who suffer from food noise, a constant urge to eat feel a huge psychological relief from the drug.

飢餓感很大程度上是基因決定的，所以特別是那些飽受食物噪音困擾、不斷想吃東西的人，能從藥物中獲得巨大的心理舒緩。

Finally, their body stopped screaming at them.

終於，他們的身體不再對他們尖叫。

Suddenly you're dieting without expending willpower, without really thinking about it.

突然間，你就能減肥，不需要消耗意志力，也不用真的去想這件事。

這感覺就像是魔法般毫不費力。

By changing your biology, a drug changed your behavior.

透過改變你的生理機能，藥物改變了你的行為。

Miracle Drugs Many people try a crash diet at some point in their lifetime.

奇蹟藥物 許多人一生中都會嘗試極端的節食法。

And it's not that crash diets don't work.

而且並不是說極端的節食法沒效。

You can lose 20% of your in three months from 95 to 75 kilos, or 130 to 105.

你可以在三個月內從 95 公斤減到 75 公斤，或是從 130 磅減到 105 磅，減掉 20% 的體重。

But such a sudden drop is not very healthy, and

但如此劇烈的體重下降並不健康，而且

for the vast majority, the weight will come back within a year.

對絕大多數人來說，體重會在一年內回來。

Diets that are sustainable are actually not diets, but long term lifestyle changes.

可持續的飲食法其實不是飲食法，而是長期的生活方式改變。

But this is painfully slow, so a lot of people quit out of frustration.

但這過程非常緩慢，所以很多人會因為沮喪而放棄。

And among those disciplined enough, Results are pretty modest.

而就算是有毅力的人，成效也相當有限。

The new drugs change that completely in three months.

而這種新藥在三個月內就徹底改變了這個情況。

You can lose 10% of your initial weight three months later, over 15 and after a year, you may reach more than 20%, a level of weight loss that used to only really be achievable through bariatric surgery.

三個月後，你可能會減掉初始體重的 10%，一年後甚至可能達到 20% 以上，這是以前只有透過減重手術才能達到的程度。

In other words, GLP1 drugs make excess weight melt away like nothing before.

換句話說，GLP1 藥物能讓多餘的體重前所未有地消失。

We can't stress enough how unhealthy obesity is, causing everything from diabetes to heart attacks and cancer.

我們再怎麼強調肥胖對健康的危害都不為過，它會引發從糖尿病到心臟病和癌症等各種問題。

So the consequences for health are stunning.

Treatment with semaglutide cuts your risk of stroke or heart attack by 20%.

使用 semaglutide 治療能將你中風或心臟病的風險降低 20%。

17 months of tirzepatide crashes your chances of developing diabetes by 66%.

使用 tirzepatide 17 個月能將你罹患糖尿病的機率降低 66%。

They also reduce sleep apnea, improve kidney and liver function, lower inflammation, cut cancer risk, and

它們還能改善睡眠呼吸中止症、提升腎臟和肝臟功能、降低發炎、減少罹癌風險，並且

They might even boost fatigue fertility, as obesity often disrupts hormones and increases complications during pregnancy.

它們甚至可能提升生育力，因為肥胖常會干擾荷爾蒙並增加懷孕併發症。

And there may be more positive long term effects.

而且長期下來可能還有更多正面影響。

Some of these benefits are a direct result of weight loss, but

其中一些好處是減重直接帶來的，但

intriguingly, they sometimes occur regardless of how much weight has been lost.

有趣的是，有時候這些好處出現時，體重並沒有減輕多少。

And some have been seen in patients who weren't obese to begin with.

甚至在原本就不是肥胖的病患身上也觀察到一些效果。

it seems like Turning up the GLP1 signal is synchronizing the whole metabolic orchestra, restoring a balance between brain, gut and body.

似乎是啟動 GLP1 訊號，讓整個代謝系統協調運作，恢復大腦、腸道和身體之間的平衡。

And as if that weren't enough, GLP1 drugs may also quiet other cravings.

好像這樣還不夠，GLP1 藥物還可能抑制其他慾望。

They seem to reduce the use of alcohol, nicotine, cannabis and opioids.

它們似乎能減少酒精、尼古丁、大麻和鴉片類藥物的濫用。