Name: 狗狗研究有望揭示人類與毛孩的長壽健康之道｜60 分鐘 (Studying dogs may reveal path to longer, healthier life for dogs, humans | 60 Minutes)
Uploaded: 2026-03-23T21:37:16.000Z
Duration: 13 min 14 s
Description: 【看影片學英語】數萬部 YouTube 影片，搭配英漢字典即點即查，輕鬆掌握單字發音與用法，長久累積看電影不必再看字幕。

Everyone knows the old adage about dogs being man's best friend,

大家知道那句老話，說狗狗是人類最好的朋友，

情態助動詞 B1

but you may not know that dogs might also be one of man's best hopes to treat age-related illnesses.

但你可能不知道，狗狗或許也是人類對抗老化疾病的一大希望。

轉承詞

That's because our canines develop many of the same diseases we do, including dementia.

這是因為我們的狗狗會罹患許多和我們一樣的疾病，包括失智症。

Dogs' brains are a lot like ours, so studying how dementia and other diseases naturally progress in them may also help us.

狗狗的大腦跟我們很像，所以研究牠們失智症和其他疾病的自然病程，可能也會幫助到我們。

That's what the Dog Aging Project is all about: unlocking secrets to a longer, healthier life for humans and our four-legged friends.

這就是「狗狗老化計畫」的宗旨：解開人類和我們四條腿的朋友活得更長、更健康的祕密。

At hundreds of vet clinics and hospitals around the country, including here at Colorado State University College of Veterinary Medicine and Biomedical Sciences, people are bringing in their dogs.

在全國數百家獸醫診所和醫院，包括這裡的科羅拉多州立大學獸醫與生物醫學科學學院，人們正帶著他們的狗狗前來。

The Dog Aging Project is a collaboration of dog owners, scientists,

Dog Aging Project 是一個由飼主、科學家

and veterinarians studying dogs, more than 50, 000 of them so far, by collecting data on their diets and exercise, analyzing blood samples,

和獸醫合作的計畫，他們研究了至今超過五萬隻狗狗，方法是收集牠們飲食和運動的數據、分析血液樣本

以及為狗狗的腦部進行 MRI 掃描。

Matt Cabraline, a biologist who spent decades trying to understand and reverse the causes of aging, co-founded the project in 2014.

Matt Cabraline，一位花了數十年試圖理解並逆轉老化原因的生物學家，在 2014 年共同創立了這個計畫。

Where did the idea of the Dog Aging Project come from?

Dog Aging Project 這個想法是怎麼來的？

I had this light bulb moment, which I still remember vividly.

我當時靈光一閃，至今仍清晰記得。

I realized, oh, my God, we know about three or four or five ways to slow aging in laboratory animals.

我意識到，天啊，我們知道有三、四、五種方法可以在實驗動物身上減緩老化。

其中一些方法應該也適用於狗狗。

我一點也不懷疑這是有可能的。

The biology of aging is so conserved or shared across the animal kingdom.

老化的生物學在整個動物界中是如此的保守或共享。

其中很多在狗狗身上也是一樣的。

其中很多在人類身上也是一樣的。

To help study how the brain ages, Cabraline recruited Stephanie McGrath, a veterinary neurologist from Colorado State University.

為了幫助研究大腦如何老化，Cabraline 找來了來自科羅拉多州立大學的獸醫神經學家 Stephanie McGrath。

I think a lot of people would be surprised to know that there are neurologists for animals.

我想很多人會驚訝地發現，原來有動物專門的神經學家。

And you believe looking at dogs and looking at dogs' brains can help us not only help dogs but humans as well?

而且你相信，透過研究狗狗和大腦，不僅能幫助狗狗，也能幫助人類，對嗎？

Because right now we are using mice, and we are putting them through treatment trials,

因為我們現在用的是老鼠，然後讓牠們接受治療試驗，

I've read that as many as 90% of the things that work in mice do not end up working in humans.

我讀到，高達 90% 在老鼠身上有效的方法，最終卻無法在人類身上奏效。

So to have something in between would be hugely beneficial.

所以，如果能有中間的步驟，將會非常有幫助。

a species that very closely mimic naturally occurring diseases of aging in humans.

一個能非常貼近人類老化時自然發生的疾病的物種。

Cancer, dementia, all these diseases that we see as humans age occur in dogs.

像是癌症、失智症，這些人類老化時會出現的疾病，在狗狗身上也會發生。

One reason they live alongside us and are exposed to the same environments.

其中一個原因就是牠們跟我們一起生活，也暴露在相同的環境裡。

They exercise with us, eat our food, drink the same water.

牠們跟我們一起運動，吃我們的食物，喝我們一樣的水。

Also key, McGrath says, is the fact that dogs have shorter lives because they age faster than humans.

McGrath 也提到，另一個關鍵是狗狗的壽命比較短，因為牠們老化的速度比人類快。

We can get a ton of information that would take decades to do in humans.

這樣我們就能獲得大量資訊，這在人類身上可能需要數十年才能完成。

In a human being, if you wanted to do a lifelong study, obviously you would have to do it from the age of 1 to 60, 70, 80.

對人類來說，如果想做一個終身研究，當然得從 1 歲做到 60、70、80 歲。

So we just check to make sure his sensory is good.

所以我們就檢查一下，確保牠的感官功能都正常。

McGrath has been tracking hundreds of dogs to see how their cognitive ability changes as they age, including 12-year-old Murphy, a German Shepherd pudel mix.

McGrath 正在追蹤數百隻狗狗，觀察牠們的認知能力隨著年齡增長如何變化，其中包括 12 歲的牧羊犬貴賓犬混種犬 Murphy。

He gets his puppy zoomies about once a week now versus once a day.

牠現在大約一週會嗨一次，以前是一天一次。

For Pat Schultz, like many of the dog owners we met, enrolling Murphy in the Dog Aging Project was personal.

對 Pat Schultz 來說，就像我們遇到的許多狗狗飼主一樣，讓 Murphy 參加狗狗老化計畫是出於個人因素。

Her husband, Bill, suffered from Alzheimer's disease, progressing to the point he stopped recognizing Pat as his wife.

她的丈夫 Bill 罹患阿茲海默症，病情進展到他不再認得 Pat 是他的妻子。

Throughout his decline, Murphy was Bill's constant companion.

在他病情惡化的過程中，Murphy 一直是 Bill 最忠實的陪伴。

Murphy 在某方面來說就像個照護者。

I have a tracking collar on Murphy, so as long as Murphy had that tracking collar on, I knew where Bill was.

我幫 Murphy 裝了追蹤項圈，只要他戴著，我就知道 Bill 在哪裡。

So while Bill is dealing with Alzheimer's, you hear about the Dog Aging Project.

所以當 Bill 在對抗阿茲海默症時，你聽說了 Dog Aging Project。

I think I was looking at clinical studies, and I found something about dog studies.

我想我當時在看臨床研究，然後我發現了一些關於狗狗的研究。

我以前從來沒聽過這些，你知道嗎？

and knowing that he's a big dog, they don't have as long a lifespan, usually.

而且知道他是一隻大型犬，牠們的壽命通常比較不長。

For the past three years, Murphy has undergone testing to assess his physical and mental fitness.

過去三年來，Murphy 接受了評估他身心健康的測試。

In games like these, dogs are shown where a treat is hidden and seconds later allowed to go and get it.

在像這樣的遊戲裡，狗狗會被訓示藏零食的地方，幾秒鐘後就可以去找。

When it was Murphy's turn, he struggled, wanting to stay with Pat, too anxious to do the test.

輪到 Murphy 時，牠很掙扎，想跟 Pat 待在一起，太焦慮而無法進行測試。

On the second try, he got a little turned around but eventually found the treat.

第二次嘗試時，牠有點轉圈圈，但最後還是找到了零食。

The anxiety that Murphy showed, is that a potential sign of dementia?

Murphy 表現出的焦慮，會不會是失智症的潛在徵兆？

In the last few visits at CSU, he's really progressed in terms of his challenges with his tasks, both here and at home.

在 CSU 過去幾次的探訪中，他在家裡和這裡的任務挑戰上，都有很大的進步。

另一隻狗狗 Ralph 也接受了測試。

At 14, he's already shown signs of advanced dementia.

他 14 歲了，已經出現了嚴重失智症的跡象。

Ralph quickly forgot about the treat, wandered off, and picked up a piece of lint off the floor.

Ralph 很快就忘了零食，跑開了，然後撿起地上一點點的棉絮。

All the information collected in the Dog Aging Project, including from these tests, goes into a public database accessible to researchers around the world.

Dog Aging Project 收集到的所有資訊，包括這些測試的結果，都會進入一個公開的資料庫，供全世界的研究人員取用。

It's been used in more than 50 scientific studies so far, many of which found correlations between lifestyle, environment, and

到目前為止，它已經被用於 50 多項科學研究，其中許多研究發現了生活方式、環境和