Name: 迷幻藥的工作原理，6分鐘內解釋清楚|馬修-約翰遜 (How psychedelics work, explained in under 6 minutes | Matthew Johnson)
Uploaded: 2022-11-01T18:27:45.000Z
Duration: 5 min 37 s

- Every psychological experience has a biological correlate:

- 每一種心理體驗都有一個生物學上的關聯。

there's something happening in your brain

that's coding that experience of the color green.

the biggest divide is whether we're talking about

on the psychological side or the biological side.

Does it work by hitting these brain receptors

它是否通過打擊這些大腦受體而發揮作用？

Or does it work because of the experience?

Clearly, there's this very real biological effect.

很明顯，有這種非常真實的生物效應。

when you put the psychedelic in the system,

and when they change their life because of that,

以及當他們是以而改變他們的生活。

they went through a really good course of psychotherapy.

他們經歷了一個非常好的心理治療過程。

at that bridge between the biological and the psychological.

在生物學和心理學之間的橋樑。

What 'psychedelic' means from its linguistic roots

從語言學的根源看 "迷幻 "的含義

The idea that these are mind manifesting-

你可能會有一個地獄般的經歷。

Also, terminology is so difficult in this area.

另外，在這個領域，術語是如此困難。

to what are called the "classic psychedelic compounds":

迷迭香，它存在於神奇的蘑菇中。

They affect a particular type of serotonin receptor

它們影響一種特定類型的5-羥色胺受體

and that's their primary mechanism of action.

that I think it's appropriate to call them psychedelic;

我認為稱他們為迷幻的人是合適的。

So for example, MDMA will work by releasing serotonin.

是以，例如，MDMA將通過釋放5-羥色胺而發揮作用。

And you have other drugs such as ketamine and PCP.

而且你還有其他藥物，如氯胺酮和五氯苯酚。

in the brain primarily rather than the serotonin system.

主要在大腦中，而不是在5-羥色胺系統中。

if it refers to multiple pharmacological classes of drugs

And the answer for me is that these are all drugs

that can have a profound effect on one's sense of reality,

這可以對一個人的現實感產生深遠的影響。

The huge question that's always thrown out is:

And you can just come at that from so many different angles.

你可以從許多不同的角度來看待這個問題。

which people may know is the active agent

Once it's circulating through your blood,

it actually converts to a related compound called psilocin,

它實際上會轉化為一種相關的化合物，稱為西洛因。

which is the thing that's actually hitting

And it activates a subtype of serotonin receptor.

而且它能激活5-羥色胺受體的一個亞型。

of different types of serotonin receptors in our brain.

我們大腦中不同類型的5-羥色胺受體。

One is called the 'serotonin 2A' receptor,

其中一個被稱為 "5-羥色胺2A "受體。

and psilocybin and the other classic psychedelics,

和迷幻藥以及其他經典的迷幻藥。

與我們的血清素鎖住的方式相同

but then serotonin affects the glutamate system.

但隨後5-羥色胺影響穀氨酸系統。

you have this massive increase in communication,

across these different silos in the brain.

That is probably an important level of analysis

that is underlying at the psychological level:

patients who have claims of insight viewing themselves

in the system so that in the days following

在系統中，以便在隨後的日子裡

people are more primed to learn new things.

There's a greater ability to establish a new

It's not just about hitting a certain type

字幕列表影片播放

迷幻藥的工作原理，6分鐘內解釋清楚|馬修-約翰遜 (How psychedelics work, explained in under 6 minutes | Matthew Johnson)

perspective

specific

massive

mental