You know, up until that time, there have been 23 outbreaks of Ebola, very small in relative terms, until this giant outbreak occurred in West Africa, and I know you've heard a lot about that, so I won't dwell on it, but suffice to say that the main issue here again is incursion, where we have people moving closer to vectors in this case bats, um, and the spill over into the primate population, or perhaps other mammals, and then the, um greater and greater connection with people and intermediate hosts or the reservoir.