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  • - Hey folks, welcome to today's Wednesday Checkup,

  • where we're gonna have some fun

  • and try and create a plague to take over the world.

  • (intense music) (static crackles)

  • (heartbeat beeps)

  • (logo sizzles)

  • Plague Inc: Evolved.

  • I've never played the original Plague Inc,

  • but I've seen a lot of requests for this

  • and this is actually a really popular video game.

  • For players wanting a quick game.

  • No one washes their hands, researchers, doctors don't work,

  • sick people give hugs.

  • Normal, 67.3% of people wash their hands,

  • doctors work three days a week, sick people ignored.

  • Brutal, compulsive hand washing, doctors never go home,

  • sick people locked in prison.

  • Mega Brutal, genetic drift impacts evolution,

  • doctors invest in research, random medical checkups.

  • I guess, let's do Casual just to get a quick game,

  • to learn how this bad boy works.

  • Name your plague, DM-V4.

  • (laughs) I dunno why V4 but now it sounds scary.

  • All right, you are a new bacteria.

  • To win you must evolve and spread across the world,

  • wiping out all humans in the ultimate plague.

  • Select start location.

  • Select a country to begin your plague.

  • When you select it with the R2 button,

  • you can see more information.

  • Pop the start bubble with R2 to confirm,

  • or select another country instead.

  • Use the left stick to move the crosshair.

  • Okay, world population 7.1 billion.

  • Where should we start this?

  • I feel like I don't want the plague

  • to kill anyone on the North-East coast of the United States,

  • so I won't start there.

  • You know what?

  • Lets target the motherland. (laughs)

  • Russia, population 160 million,

  • there is planes, there's ships,

  • it's rainy, it's snowy, lots of leaves.

  • DM-V4 has infected its first human.

  • Weak but used to cold temperatures,

  • it must evolve using DNA points to infect more people.

  • I've infected one person with zero dead.

  • There's airplanes flying all around.

  • Okay, if I do Blood 1, gives organism ability

  • to spread to blood-to-blood contact.

  • Water 1, pathogen can survive outside

  • in fresh, warm water.

  • That's definitely not good for Russia

  • cause there's no warm water.

  • Air 1 gives pathogen ability to travel on dust particles.

  • Common flea, no we don't want rodents.

  • Birds, insects, I say blood through blood contact,

  • that's probably the best for Russia.

  • Oh, symptoms.

  • Painful cysts containing pockets of the pathogen,

  • slight chance of bursting which can spread disease.

  • And that costs two DNA points,

  • I currently have three, let's evolve.

  • Woo, look at that evolving happening!

  • You have spent DNA points to evolve your disease

  • and more options have opened up.

  • Get more points by popping DNA and Biohazard bubbles

  • with R2 and infecting people.

  • I don't get--

  • Oh, I popped.

  • Oh, I just got DNA points!

  • Okay, time to make this a bloodborne pathogen.

  • Yeah!

  • Oh, this is gonna be bad.

  • Okay, DM-4 has infected hundreds of Russia,

  • increasing the chance that a infected person

  • will infect a healthy person.

  • Keep evolving your disease, cool.

  • See, I wanna go for Blood 2 because then

  • we can infect bodily fluids and get mucus membranes going.

  • It's gonna be like the flu.

  • We're gonna make DM-V4 like the flu but with cysts.

  • This is really weird.

  • Ooh, I like this.

  • If they can get an abcess, pockets of infected flesh

  • are painful and act as breeding grounds for the pathogen,

  • increasing infection sites, yeah.

  • Ooh, we got abilities.

  • Pathogen evolves, yes!

  • We need cold resistance, 'cause in Russia,

  • it's freezing, trust me on this.

  • I've never thought I would be so excited

  • about infecting the world.

  • DM-V4 has infected thousands in Russia.

  • People are being infected faster and faster, yeah.

  • 22,000, 23,000, okay.

  • Oop, medicine in Norway slowing infection.

  • Norway's a wealthy country with high quality health care.

  • To spread faster, you may need to evolve

  • the drug resistance ability.

  • Norway, you got good health care but I'm coming.

  • DM-V4 is beginning to spread around the world.

  • Hit the Triangle button to see which countries are infected.

  • Wow, look at that, we got Norway, Finland, Russia,

  • Ukraine, Turkey, Iran, Kazakhstan, China.

  • I'm gonna create drug resistance

  • to make sure Norway doesn't start catching up to me.

  • I already got 2,000,000 infected.

  • DM-V4 has infected more people in the world than TB.

  • It is a very infectious disease.

  • My god, look at the country being wiped out.

  • 21,000,000 people, two dead.

  • I've claimed my first victim.

  • This is making me happy for a really strange reason.

  • Russia is the first to instruct doctors

  • to begin research into a cure for DM-V4.

  • The more scary DM-V4 becomes by hurting and killing people,

  • the harder humans will try and cure it.

  • Remember this when evolving your disease.

  • Oh, no, we have a million dead as a result of my illness.

  • Russia exterminates pigeons, what?

  • What's happening in Russia here?

  • Oh my god, look at the government

  • is dispensing bottled water, exterminating rats,

  • face masks are being distributed,

  • exterminating pigeons, what do the pigeons do?

  • My god, Russia's dropped already $2,000 on medical research.

  • That's not that much money, Russia, you could do better.

  • Oop, oop we got a case in the US!

  • Do we have a case in the US?

  • Oop, 17 infected.

  • All right, poor Russia is just all red on this map.

  • Greenland is about to wiped out.

  • Am I gonna destroy the population of Russia right now?

  • 90% of their population's infected.

  • 10% of their population's dead.

  • All hospitals are closed, they're using mass graves.

  • Jesus.

  • Oh, it's spreading into Africa and Australia.

  • Okay, I think I'm taking over.

  • I think the world's about to end.

  • Killed more than the Black Plague.

  • We've killed over 75,000,000 people.

  • Tip: Fight the Cure.

  • There are two ways to fight development of the cure.

  • Evolve aggressive symptoms to destroy countries,

  • more noticeable,

  • or evolve cure resistance, less noticeable.

  • (gasps) The cure in the US for DM-V4 is 25% complete.

  • No way.

  • (gasps) Research doctors all over the world

  • are completely focused on developing a cure.

  • No.

  • Indonesia is leading the global cure effort.

  • They started to send research teams.

  • Pop blue bubbles to destroy their research.

  • Stop doing research.

  • They may find a cure.

  • This might be problematic.

  • 'Cause I think I infected all the countries

  • and I think I was too aggressive with it.

  • Oh, the cure of the world is 70% done.

  • You know what I need to do?

  • I need to create warm resistance so it can spread to Africa.

  • Let's see if I can get it to spread to Africa.

  • The cure is 95% complete.

  • I've only killed 362,000,000 people.

  • The cure for DM-V4 is finished

  • and it's being deployed worldwide.

  • Oh no, look at the number of infected.

  • The world has survived a devastating plague

  • and will soon eradicate DM-V4 forever.