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  • A team of MIT engineers

    麻省理工學院的一個工程師團隊

  • has designed an ingestible, expanding pill

    設計了一種可攝取進體內的膨脹藥丸,

  • that can monitor the stomach for up to a month,

    它可以監控胃部達一個月的時間,

  • potentially tracking cancers, ulcers

    可能可以追蹤癌症、潰瘍

  • and other GI conditions.

    和其他胃腸道疾病。

  • Soft and squishy, it's made from two types of hydrogels,

    藥丸既柔軟又濕黏,以兩種水凝膠製成,

  • the combination of which enables the pill to quickly swell

    而水凝膠的組合使藥丸迅速膨脹,

  • while remaining impervious

    同時能在胃部的酸性環境中

  • to the stomach's acidic environment.

    保持不受影響。

  • If the patient needs to remove the pill,

    如果患者需要取出藥丸,

  • they can simply drink a solution of calcium ions

    他們只要飲用比全脂牛奶

  • containing more calcium than whole milk

    鈣含量更多的鈣離子溶液,

  • that triggers the pill to quickly shrink back

    這會觸發藥丸迅速收縮回

  • to its original size and pass safely out of the body.

    原來的大小並安全地排出體外。

  • This hydrogel based design is softer, more bio-compatible

    這種以水凝膠為基底的設計比目前

  • and longer lasting than current ingestible sensors,

    可攝取進體內的傳感器更柔軟、更俱生物相容性並且更耐用,

  • typically made of hard plastics or metals

    而一般的傳感器是由硬塑料或金屬製成,

  • which are quite stiff in comparison

    與胃腸道相比顯得

  • to the gastrointestinal tract.

    十分堅硬。

  • The inner material of the design

    這款設計的內部材料

  • are super absorbent hydrogel particles

    是具有極強吸水力的水凝膠顆粒,

  • that are used in commercial products such as diapers

    這種顆粒因其迅速吸收液體的能力,

  • for their ability to soak up liquid quickly.

    會被用於像是尿布這類的商品。

  • The second protective hydrogel layer was designed

    第二層的保護性水凝膠層是設計用來

  • to encapsulate the fast swelling particles.

    把快速溶脹的顆粒封進內部的。

  • The outer membrane is made from a multitude

    膜的外層由多個

  • of nanoscopic crystalline chains, each folded over another

    奈米級晶體鏈製成,每個晶體鏈皆以幾乎不可穿透的網格狀

  • in a nearly impenetrable gridlock pattern.

    彼此摺疊著。

  • To test the inflatability of the design,

    為了測試此款設計的膨脹性,

  • researchers dumped the material in various solutions

    研究人員將其材料倒進各種

  • of water and fluid resembling gastric juices.

    類似胃液的水和液體溶液中。

  • They found the pill inflated

    他們發現藥丸

  • up to a hundred times its original size in about 15 minutes,

    在大約15分鐘內膨脹到其原始大小的一百倍,

  • much faster than existing expandable hydrogels.

    速度比現有的可膨脹水凝膠快得多。

  • To test the pill's toughness,

    為了測試藥丸的堅韌度,

  • the researchers mechanically squeezed it thousands of times

    研究人員用比藥丸可能會在胃部經歷的常規收縮

  • at forces greater than the pill would ever experience

    大上一千倍的力量

  • for regular contractions in the stomach.

    機械式地去擠壓它。

  • They found the design is both soft like tofu or jello

    他們發現這款設計像豆腐或果凍一樣柔軟,

  • but extremely robust.

    卻極度堅固耐用。

  • Finally, to show their ability

    最後,為了要展現其

  • to track environmental changes in the stomach,

    追蹤胃部環境變化的能力,

  • the researchers embedded

    研究人員在設計中嵌入了

  • within their design a small commercial temperature sensor

    一個小型工業用溫度傳感器,

  • which allows them to accurately

    這能讓他們準確

  • and remotely track activity patterns within the body

    並遠程追踪身體內的活動模式,

  • for up to 30 days.

    最久可達30天。

  • Down the road, the researchers envision the pill

    在未來,研究人員預期這款藥丸

  • may safely deliver a number of different sensors

    可以安全地傳遞許多不同的傳感器

  • to the stomach to monitor for instance pH levels

    到胃部去監測像是酸鹼值

  • or signs of certain bacteria or viruses.

    或者某些細菌或病毒的徵兆。

  • Tiny cameras may also be able to be embedded into the design

    隨著時間的發展,微型相機也許可以嵌入此款設計,

  • to image the progress of tumors or ulcers over time.

    以令腫瘤或潰瘍的進程成像。

A team of MIT engineers

麻省理工學院的一個工程師團隊

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