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  • Voiceover: Imagine you're in a movie theater.

  • You're watching a really, really long movie.

  • And you've finished your entire bucket of popcorn.

  • You've guzzled down a giant soda

  • and all of a sudden, you have to pee.

  • And to make matters worse, you're watching a movie

  • about a whole bunch of people on a cruise ship

  • that hit an iceberg and so, there's a lot of water

  • in this movie and you freak out because

  • now you have to get up and go to the bathroom.

  • But then that should get you thinking,

  • well, how do my kidneys work?

  • How is it that I can make all this pee

  • that I have got to get rid of?

  • Well in the next few videos, we're gonna

  • talk about how the kidneys work.

  • And I'll give a quick overview here

  • before we delve more into the specifics.

  • As you can see, the kidneys sit

  • right here around your belly button.

  • They're about the size of a fist and you've got two of them.

  • And they sit a little closer

  • to the back, not really in the front.

  • So the kidneys receive blood from the heart.

  • So the heart goes on up here.

  • It's also about the size of a fist.

  • And it pumps blood throughout the body.

  • You know, you get some to your arms,

  • you have some that goes up to your brain,

  • and you have this branch that comes down

  • and it goes towards your legs, as well.

  • Well, what you can kind of see

  • in the picture of the kidneys right here,

  • is that they've got a little vessel right there

  • so sure enough, there's some blood that comes

  • from the heart into the kidneys.

  • Both of your kidneys, then, are going to

  • filter the blood and release urine,

  • which is just a collection of waste products

  • that your body wants to get rid of.

  • And the urine is gonna hang out

  • in your bladder that sits about right here,

  • until it's an appropriate time to go to the bathroom.

  • And that's kind of a broad overview.

  • But let's go into a little more detail

  • about what the kidneys do.

  • So I'm going to draw a box over here.

  • And this box is going to be what the kidneys do.

  • So I'm going to give just a really simplistic

  • overview of what the kidneys do.

  • And then in other videos, we'll go dive deeper into detail.

  • So as I mentioned, each of your kidneys

  • gets an oxygenated blood vessel,

  • or an artery that goes to them.

  • And your arteries hold onto all the things in your blood.

  • This can include things like your nutrients.

  • And so nutrients can be anything from say,

  • your electrolytes like your sodium ions.

  • They can be things like your proteins or your

  • amino acids or even glucose, as well,

  • things that build your carbohydrates.

  • So a lot of things that your body uses

  • as the building blocks, or things that help

  • other structures of your body work.

  • In addition to your nutrients, you've also got

  • oxygen hanging out in your arterial blood.

  • And your arteries also contain waste products.

  • So things your body has made through cellular respiration

  • and all these other processes that we undergo

  • that we don't need anymore, that we want to get rid of.

  • And they can include things like urea and other

  • toxic compounds that we don't want to build up.

  • And at the same time, it can also include

  • extra electrolytes, like sodium that we don't need.

  • Because if we hold onto a lot of sodium chloride,

  • which is just salt, we'll end up having high blood pressure.

  • So our kidneys also help us maintain our

  • blood pressure, as we'll talk about in other videos.

  • So, this just kind of underlines

  • the point that if you have too much

  • of your nutrients, they become waste products.

  • And so, your kidneys help to make sure you don't

  • build too much of this good stuff here.

  • So this is all the stuff you've got hanging out

  • in the artery that's coming over to your kidney, right here.

  • And as you might recall, whenever you have

  • an artery coming into an organ or a part of your body,

  • there should be a vein that takes the blood away

  • from it that's going to return it to the heart.

  • So this is your vein, right here.

  • And so the job of the kidneys then, is to make it so that

  • the nutrients you had in your arterial blood

  • are collected and maintained when we get to the vein.

  • So we want to hold on to our nutrients, right here.

  • So I'll just write "nutrients".

  • And it stands for all the stuff that I

  • gave examples for on the left side here.

  • And the kidneys, like every organ

  • in the body, need oxygen to do well.

  • So you'll have the oxygen go through the kidneys

  • and some of it will make it out.

  • Some of it will be used by the kidneys.

  • Because that's how we can maintain some of the tissue.

  • And so when we get to the other side,

  • where the vein is, we'll have less oxygen.

  • So I'll write it really tiny right here to show

  • that there's much less oxygen in your venous blood

  • than there was in your arterial blood.

  • And finally, the kidneys want to take all the

  • waste products your arterial blood brought

  • to the kidney and hold on to it, make it so that

  • this stuff does not end up in the venous outflow.

  • And by collecting these waste products,

  • the kidneys will effectively produce your urine.

  • Now, you might notice in this picture

  • that I am missing something.

  • What connects the artery to the vein?

  • Well actually what goes on here

  • is part of what makes the kidney so special.

  • And it answers the "how".

  • How is it that the kidneys are able to do this?

  • How is it that the kidneys can help us

  • maintain our nutrients in our body

  • while getting rid of waste into urine?

  • Well, the kidney is special

  • because it's got two capillary beds.

  • I think you might have heard

  • what a capillary is before, alright?

  • A capillary bed is just something that

  • connects the artery and the vein.

  • It's where you can have oxygen flow out.

  • You can have nutrients flow in.

  • So the way I'll draw it is that you've got one

  • capillary bed, right here, connecting your

  • artery to your vein, like that.

  • And you've got another one down here connecting those two.

  • And so these guys work together to deliver oxygen

  • to the kidney's tissue and, at the same time,

  • recollect these nutrients so that the vein can

  • take these nutrients elsewhere in the body for use.

  • And these capillary beds have two fancy names.

  • The first one is called the vasa recta.

  • The vasa recta.

  • And that's mainly to give oxygen to the kidneys.

  • The other set of capillaries are

  • called peritubular capillaries.

  • Peritubular capillaries, and we'll talk way more

  • into detail about these peritubular capillaries.

  • And these are the guys that are mainly

  • going to be responsible for collecting

  • nutrients that our kidneys will filter.

  • And we'll talk more about that

  • process in the next few videos.

Voiceover: Imagine you're in a movie theater.

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