Name: 【TED-Ed】安慰劑效應的力量 (The power of the placebo effect - Emma Bryce)
Uploaded: 2016-09-28T23:00:00.000Z
Duration: 4 min 38 s
Description: 有沒有聽過安慰劑效應？病人就算得到毫無效果的治療，只要他相信療效，病情竟然能很神奇地舒緩！來一起探索這背後的原因吧！ 1phenomenon00:46 phenomenon 可以指「現象」，例如科學現象、心理現象等等。要注意， phenomenon 的複數是 phenomena 。 Whale stranding is...

In 1996, 56 volunteers took part in a study

1996 年時，56 位自願者參與一項研究

to test a new painkiller called Trivaricaine.

以測試一種新的止痛藥， 名叫 Trivaricaine

On each subject, one index finger was covered in the new painkiller

每個實驗對象的一隻食指都被塗上新的止痛藥

Then, both were squeezed in painful clamps.

而後，兩隻食指都用會致痛的鉗子夾緊

The subjects reported that the treated finger hurt less than the untreated one.

實驗對象敘述塗藥食指較沒塗藥的不痛

except Trivaricaine wasn't actually a painkiller,

但是事實上，Trivaricaine 不是止痛藥

just a fake concoction with no pain-easing properties at all.

只是一種毫無止痛功效的假混合物

What made the students so sure this dummy drug had worked?

是什麼讓學生如此肯定這假藥有效呢？

wherein drugs, treatments, and therapies that aren't supposed to have an effect,

在原本應無效的藥物、治療及各種療法

Doctors have used the term placebo since the 1700s

自 1700 年代起， 醫生已使用「安慰劑」這個詞

when they realized the power of fake drugs to improve people's symptoms.

當時他們已了解假藥改善病人症狀的效力

These were administered when proper drugs weren't available,

或有人幻想自己生病時， 醫生會使用安慰劑

In fact, the word placebo means "I shall please" in Latin,

事實上，安慰劑在拉丁文 是「我會使你滿意」之意

hinting at a history of placating troubled patients.

隱喻它撫慰受折磨的病人由來已久了

Placebos had to mimic the real treatments in order to be convincing,

安慰劑必須酷似真的治療以取信病人

Soon, doctors realized that duping people in this way had another use:

很快地，醫生了解此種欺瞞人們方式有另一用途：

By the 1950s, researchers were using placebos as a standard tool

1950 年代之前，研究人員已用安慰劑

half the patients in a trial might receive the real pill.

實驗中的一半病人可能服用真藥

The other half would get a placebo that looked the same.

另一半則服用外觀一樣的安慰劑

Since patients wouldn't know whether they'd received the real thing or a dud,

既然病人都不知道服用的是真的或無用的

the results wouldn't be biased, researchers believed.

Then, if the new drug showed a significant benefit compared to the placebo,

如果相較於安慰劑， 新藥呈現有顯著的功效

Nowadays, it's less common to use placebos this way because of ethical concerns.

現今已較少這樣使用安慰劑， 由於有道德上的疑慮

If it's possible to compare a new drug against an older version, or another existing drug,

如果可能以新藥比較舊型的藥或另一現有的藥

that's preferable to simply giving someone no treatment at all,

especially if they have a serious ailment.

In these cases, placebos are often used as a control to fine-tune the trial

這些情況下，安慰劑常被作為微調實驗的控制項

so that the effects of the new versus the old or alternative drug can be precisely compared.

讓新型、舊型或替代藥的效用可被精確地比較

But of course, we know the placebos exert their own influence, too.

但當然， 我們知道安慰劑也發揮本身的作用

patients have experienced relief from a range of ailments,

even though all they'd received was a fake drug or sham surgery.

即使他們所接受的完全是假藥或模擬手術而已

the placebo effect is merely confused with other factors,

安慰劑效應只不過和其他因素相混淆而已

like patients trying to please doctors by falsely reporting improvements.

例如病人為取悅醫生而作症狀改善的不實敘述

researchers think that if a person believes a fake treatment is real,

研究人員認為若一個人相信假治療是真的

their expectations of recovery actually do trigger physiological factors

他們期待康復的心理會真正激起一些生理因子

Placebos seem to be capable of causing measurable change in blood pressure, heart rate,

and the release of pain-reducing chemicals, like endorphins.

及止痛化學物質的釋放── 例如內啡肽（endorphin）有明顯改變

That explains why subjects in pain studies often say placebos ease their discomfort.

這說明疼痛實驗中，為何實驗對象常說安慰劑舒緩他們的不適

Placebos may even reduce levels of stress hormones,

安慰劑甚至可降低壓力賀爾蒙的數值

which can slow the harmful effects of an ailment.

So shouldn't we celebrate the placebo's bizarre benefits?

所以我們不該頌揚安慰劑的奇特效益嗎？

If somebody believes a fake treatment has cured them,

如果有人認為假治療已治癒他們

they may miss out on drugs or therapies that are proven to work.

他們可能錯過使用真正有效藥物或治療的時機

Plus, the positive effects may fade over time,

另外，這正面效用可能隨時間逐漸消失

making scientists even more motivated to discover

它們是如何有這能力操控我們的

Despite everything we know about the human body,

there are still some strange and enduring mysteries,

So what other undiscovered marvels might we contain?

所以我們還有什麼其他未發現的奇蹟嗎？

It's easy to investigate the world around us

我們很容易在研究周圍的世界時

and forget that one of its most fascinating subjects