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  • This episode of Dnews was proudly made possible by the all-new 2015 Subaru Legacy. It’s

    這一集 Dnews 很榮幸由2015年全新的 Subaru Legacy 贊助

  • not just a sedan, it’s a Subaru.

    這不只是轎車,還是Subaru轎車呢

  • You know those people who claim that they actually ENJOY exercise? Well it turns out,

    你有認識誰說自己很「享受」運動嗎?而且後來發現

  • they may be right. Damn it.

    他們真的如此,可惡!

  • Hey guys, Tara here for Dnews - and try as we might, some of us just seem predisposed

    嗨,大家好,我是Dnews的Tara,有些人似乎更容易

  • to loving exercise. You get addicted to the endorphins, they say - and even though I personally

    愛上運動,他們會說自己腦內啡上癮- 雖然我本身

  • can’t understand what that’s like, it turns out there IS a part of our brains dedicated

    不了解這是怎樣,但是我們大腦某部分「的確」需要這個東西

  • to that - and it may explain why some people are more motivated to exercise than others.

    這也許能解釋,為什麼有些人比別人更有動力去運動

  • Scientists at the Seattle Children’s Research Institute have discovered a tiny region of

    西雅圖兒童研究機構的科學家發現老鼠腦部有

  • the brain in mice - called the dorsal medial habenula - that controls their desire to exercise.

    一小區域-叫做背內側疆- 可以控制老鼠運動的慾望

  • It’s also responsible for mood regulation and motivation, but its similarity to a structure

    這個區域也掌管情緒控制和做事情的動力,和人類大腦結構很相似

  • in human brains - means it could lead to improved treatments for depression, which typically

    這個發現有利於提升憂鬱症治療的療效,憂鬱症一般

  • coincides with a lack of motivation.

    伴隨著缺乏動力的情形

  • The link between exercise and depression - has been proven time and time again. “Changes

    運動與憂鬱症之間的關連- 也一再被證明,

  • in physical activity and the inability to enjoy rewarding or pleasurable experiences,

    「動作行為改變,覺得了無生趣、感覺不到快樂

  • are two of the hallmarks of major depression” - so it makes sense that exercise would be

    是憂鬱症主要的兩種徵狀」-所以說運動

  • one of the more effective treatments for it. But the brain pathways responsible for exercise

    為更有效的療法之一是有道理的,但是大腦負責讓人想運動的路徑

  • motivation haven’t been well understood - until now.

    還沒被完全了解- 到目前為止還沒

  • For their study, a team of researchers examined 3 different groups of mice. The first group,

    他們的研究中,一群科學家把老鼠分成三組檢視,第1組

  • was a control. The second group, was genetically engineered to have their dorsal medial habenula

    是控制組,第2群經由基因改造,阻斷他們的背內側疆

  • blocked - and the third group, were given the option of hyperactivating their dorsal

    第3組則給老鼠選擇是否強化他們的背內側疆

  • medial habenula, using laser technology.

    以雷射技術來增強

  • Sure enough, the second group, whose brain region was blocked - were much more lethargic

    可以知道,第2組腦區域被阻斷的老鼠,比起控制組更為懶散

  • than the control mice. Meaning even though they were physically capable of running on

    這個結果表示,即使老鼠有能力到輪子裡去跑步

  • their wheel - they just didn’t want to.

    他們還是不想去

  • On the flip side, the third group of mice - had the option of either activating or suppressing

    另一方面,第3組老鼠- 可選擇強化或抑制背內側疆

  • their dorsal medial habenula, by turning one of two response wheels. Turns out, mice strongly

    牠們可以滾動其中一種輪子來做不同選擇,結果顯示

  • preferred activating that area, as opposed to suppressing it. And that signifies that

    比起抑制這個區域,老鼠更加喜歡強化它,這也意味

  • this part of the brain is strongly tied to rewarding behavior.

    大腦這個區域跟獎勵行為有很大關聯

  • It makes sense that the mice would choose that option, too. After all, nobody WANTS

    老鼠會選那邊是有道理的,總之,沒人會「想」

  • to be depressed or lazy - it’s just something that happens. So you can imagine how useful

    變沮喪或懶散-就是這樣啦,所以你可以想像一下這種藥

  • a drug would be, that specifically targets and activates that area.

    會有多大功用,可以針對這個腦區域來加強活化

  • Depression may be a well-understood disease, but the treatments for it - are still lacking.

    大家對憂鬱症已有充分了解,但治療方式-仍舊缺乏

  • So researchers hope that this discovery - can help develop better therapies for people who

    所以,研究人員希望這個發現- 可以發展出更好的治療,給那些

  • lack the motivation to help themselves.

    缺乏動力來拯救自己的病患

  • What do you guys think? Aside from the depression aspects, would you take a drug that made you

    你們覺得怎麼樣呢?先不論憂鬱症,你會想吃藥來讓自己

  • more motivated to exercise? Of course you would. Let us know your thoughts in the comments below - and as always,

    更有動力去運動嗎?在下面留言,讓大家知道你的想法- 最後,一如往常地

  • thank you guys for watching!

    感謝您的收看!

This episode of Dnews was proudly made possible by the all-new 2015 Subaru Legacy. It’s

這一集 Dnews 很榮幸由2015年全新的 Subaru Legacy 贊助

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B1 中級 中文 老鼠 憂鬱症 運動 區域 大腦 強化

懶惰是大腦的責任? (Is Your Brain Making You Lazy?)

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    羅紹桀 發佈於 2016 年 09 月 20 日
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