Name: 胚胎植入前遺傳學篩查 (PGS) 的工作原理 (How Preimplantation Genetic Screening (PGS) Works)
Uploaded: 2025-02-15T23:45:37.000Z
Duration: 4 min 7 s

For couples facing fertility issues, the road from let's do this to meeting a happy, healthy baby can be an emotional rollercoaster.

對於面臨生育問題的夫婦來說，從 "讓我們開始吧 "到迎接一個健康快樂的寶寶，這中間的過程可能會像坐雲霄飛車一樣情緒激動。

關係子句

Now, there's a test that improves the odds for parents-to-be going through in vitro fertilization treatment.

現在，有一種檢測方法可以提高準父母接受體外受精治療的機率。

A healthy pregnancy begins with a healthy embryo.

A fertilized egg contains half of mom's DNA and half of dad's.

受精卵含有一半媽媽的 DNA 和一半爸爸的 DNA。

One day after fertilization, a healthy embryo begins to form with 46 chromosomes.

受精一天後，一個擁有 46 條染色體的健康胚胎開始形成。

Sometimes an embryo has too many or too few chromosomes, causing a miscarriage or leading to birth defects.

有時胚胎的染色體過多或過少，會導致流產或出生缺陷。

This happens 40 to 50% of the time, in fact, in both older and younger couples.

事實上，這種情況在老年夫婦和年輕夫婦中都會發生，佔 40% 到 50%。

In addition to those odds, couples going through IVF face other challenges.

除了這些機率之外，接受試管嬰兒的夫婦還面臨著其他挑戰。

It can take multiple tries to get pregnant, at a high cost, financially, emotionally, and physically.

懷孕可能需要多次嘗試，在經濟、情感和身體上都要付出高昂的代價。

And when doctors transfer multiple embryos to improve the chance of pregnancy, the probability of twins, triplets, or more increases.

當醫生為提高懷孕機率而移植多個胚胎時，雙胞胎、三胞胎或更多的可能性就會增加。

That's why researchers developed Preimplantation Genetic Screening, or PGS, a highly specialized genetic test performed in collaboration with IVF clinics worldwide.

是以，研究人員開發了植入前遺傳學篩查（PGS），這是一種與全球試管嬰兒診所合作進行的高度專業化的遺傳學檢測。

PGS dramatically increases rates of implantation and live births.

PGS 能顯著提高植入率和活產率。

The test may reduce time between IVF cycles, if a second cycle is needed.

如果需要進行第二次試管嬰兒週期，該測試可縮短兩次試管嬰兒週期之間的間隔時間。

The risk of miscarriage early in pregnancy, the risk of a live birth in which the baby has a chromosomal abnormality, such as Down syndrome, and the risk, and costs, associated with multiple pregnancies.

懷孕早期流產的風險、活產嬰兒染色體異常（如唐氏綜合症）的風險以及多胎妊娠的風險和成本。

The fertilized egg divides into two cells, then four, then eight, and so on.

受精卵分裂成兩個細胞，然後是四個，八個，以此類推。

By day five, there are over 100 more distinctive cells.

到了第五天，又出現了 100 多個獨特的細胞。

One cluster of cells will become the fetus, another, the placenta.

一簇細胞將成為胎兒，另一簇細胞將成為胎盤。

An embryologist uses a small tool, 1-22nd the diameter of a human hair, to remove a few cells from the cluster that will become the placenta.

胚胎學家用一個直徑只有頭髮絲1-22分之一的小工具，從將成為胎盤的細胞團中取出幾個細胞。

That sample is overnighted to a Cooper Genomics lab for testing, while your embryo stays safe in the care of your clinic.

樣本將連夜送往庫珀基因組學實驗室進行檢測，而您的胚胎則由您的診所安全保管。

在實驗室裡，我們要做兩件事。

First, we make millions of copies of the DNA in those cells, so we have plenty to examine.

首先，我們在這些細胞中複製了數百萬個 DNA 副本，是以我們有很多東西可以研究。

Then, we count the chromosomes in each sample removed from each of your developing embryos.

然後，我們會對從每個發育中的胚胎中取出的樣本中的染色體進行計數。

This information is relayed to your clinic, where you and your doctor can make a more informed decision about treatment, and can transfer a healthy embryo.

這些資訊將轉達給您的診所，您和您的醫生可以在那裡做出更明智的治療決定，並移植健康的胚胎。

That means a dramatically better chance of starting a pregnancy, with lower risk of complications.

這意味著開始懷孕的機會大大增加，併發症的風險也更低。

Plus, other healthy embryos can be safely frozen for your future use.

此外，其他健康的胚胎也可以安全地冷凍起來，供您將來使用。

Our mission is to advance the field of reproductive genetics and empower families worldwide.

我們的使命是推動生殖遺傳學領域的發展，增強全球家庭的能力。

Cooper Genomics has already done this for tens of thousands of patients.

庫珀基因組研究公司已經為數萬名患者完成了這項工作。

If you're thinking of IVF, or have already started, ask your doctor whether PGS fits your care plan.

如果您正在考慮試管嬰兒，或者已經開始試管嬰兒，請諮詢醫生 PGS 是否適合您的治療計劃。

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胚胎植入前遺傳學篩查 (PGS) 的工作原理 (How Preimplantation Genetic Screening (PGS) Works)

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