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  • "The Diet Shown to Slow Age-Related Hearing Loss"

  • A 2021 scoping review on the role of nutrition in the development

  • and prevention of age-related hearing loss screened thousands of papers

  • and concluded thatDiets rich in saturated fats and cholesterol

  • have deleterious effects on hearing that could be prevented by lower consumption.”

  • The case of the Mabaan I noted before makes for a compelling story,

  • but on what exactly are they basing their conclusion?

  • It's true that in laboratory animals you can prove it.

  • Randomize rats to added saturated fat or chinchillas to added dietary cholesterol,

  • and scientists can show atherosclerosis-inducing diets

  • exacerbate inner ear damage and hearing loss,

  • even without noise exposure.

  • But that doesn't necessarily mean the same is true in people.

  • There is cogent epidemiological data.

  • For example, a study of thousands of twins was able to draw a significant link

  • between a high cholesterol diet and hearing impairment.

  • In the Blue Mountains Hearing Study, which enrolled thousands of older men

  • and women to study age-related hearing loss,

  • dietary cholesterol was the nutrient component

  • most associated with hearing loss.

  • Those eating about two eggs worth of cholesterol a day

  • had 34 percent greater odds of hearing loss

  • compared to those only getting about a single egg's worth.

  • Consistent with a vascular cause, those on statins,

  • and particularly those at higher doses, appeared to be at lower risk.

  • The researchers suggest that high cholesterol intake

  • may interfere with the circulation within the inner ear itself,

  • or atherosclerotic inflammatory changes could reduce blood flow

  • to the tiny arteries feeding the inner ear.

  • But how about looking inside the arteries to see if this is actually true?

  • The extent and severity of coronary artery disease in the heart,

  • as determined by angiogram, was found to closely correlate to hearing loss.

  • Since atherosclerosis is a systemic disease affecting the entire arterial tree,

  • this has relevance for the arteries feeding the inner ear.

  • The same was found for the amount of atherosclerotic plaque

  • found in the carotid arteries in the neck.

  • The greater the plaque, the poorer the hearing, and the more plaque they found,

  • the greater risk of further hearing impairment

  • measured over the subsequent five years.

  • Getting closer, but how about the arteries that directly supply the inner ear?

  • Early autopsy data suggested sclerotic changes in the blood vessels of older ears

  • contribute to inner ear degeneration, and these days,

  • direct imaging studies correlate the degree of hearing loss

  • with atherosclerotic narrowing of those inner ear arteries.

  • Now all we need is an interventional trial to wrap it all up in a bow.

  • Yes, high-cholesterol and high saturated fat diets

  • have been shown to kill off those critical inner ear cells

  • and cause hearing loss in lab animals,

  • but it's not like you can lock hundreds of people up for a few years

  • and force them to eat different amounts of saturated fat

  • and see what happens to their hearing.

  • Oh, but you can, and they did: The Finnish Mental Hospital Study.

  • In 1960, one of two mental hospitals near Helsinki had their menus changed

  • to decrease their intake of saturated animal fat.

  • Then, after a few years, the two hospitals switched their menus over.

  • It was one of the first interventional trials of its kind

  • suggesting that you could decrease heart disease deaths

  • by decreasing saturated fat intake.

  • Ah, but what happened to their hearing? It followed the exact same pattern.

  • As their heart disease got worse, so did their hearing.

  • And then when the hospitals switched, the reverse happened.

  • And not just by a little.

  • Those in their 50s in the lower saturated fat hospital

  • ended up with significantly better hearing

  • than the group in the control hospital that was ten years younger.

  • The researchers concluded: "our audiological studies lead us to conclude

  • that diet is an important factor in the prevention of hearing loss.”

"The Diet Shown to Slow Age-Related Hearing Loss"

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The Diet Shown to Slow Age-Related Hearing Loss

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    林宜悉 發佈於 2024 年 02 月 26 日
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