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  • "Supplement Regulation and Side Effects: Efforts to Suppress the Truth"

  • In a video I did a few years ago, I talked about how press releases

  • about the latest science coming out of even top medical centers

  • were filled with overstatements and omissions.

  • Medical journal press releases suffered from similar problems,

  • and press releases from the drug companies themselves

  • were no different, filled with hype and exaggeration.

  • What about press releases issued by the supplements industry?

  • Not even the companies that published the studies,

  • but like trade organizations

  • for the multi-billion-dollar dietary supplement industry?

  • Researchers found that 100% of supplements industry press releases

  • contained "spin," meaning strategies to hype or denigrate findings

  • to distort the results of clinical studies.

  • And here's the crazy part: industry press releases advocated

  • supplement use in response to more than 90%

  • of even the studies that reported no benefit or harm.

  • Here are the harm studies.

  • A study comes out showing a supplement is actually bad for you,

  • and the vast majority of independent institutions like

  • the National Institutes of Health or mainstream media stories

  • are like "don't take it." Duh. But the industry trade

  • organizations are like, "Harm? Go for it! Buy an extra bottle."

  • It is, therefore, likely that the propagation of the spin-enriched

  • industry press releases contributes to the ongoing, and even burgeoning,

  • enthusiasm for use of supplements in the face of accumulating evidence

  • of most of their ineffectiveness and, in some cases, harm.

  • In some cases, people are paying to make themselves sick.

  • Sadly, the science may not even matter to many supplement users.

  • Most dietary supplement users said that they would be minimally influenced

  • by independent, taxpayer-funded studies contradicting

  • the efficacy claims of supplement manufacturers.

  • Only a minority of users said they would stop taking a supplement

  • if public health authorities stated that it was just a waste of money.

  • The iconic image of the snake oil salesman was actually a real dude:

  • Clark "the Rattlesnake King" Stanley in 1916.

  • Turns out that Stanley's snake oil, in fact, contained no snake oil at all

  • but rather just like spicy mothballs and turpentine,

  • prosecuted under the newly enacted Pure Food and Drug Act,

  • and ultimately fined a lofty sum of $20 bucks.

  • And a century later, here we are with snake oil coming out our ears,

  • a vast number of supplements marketed and sold without routine oversight.

  • Now, the supplement industry bristles at such talk, saying that

  • the supplement industry is regulated to protect consumers.

  • And it's true there are definitely laws on the books, but the ability

  • of regulators to successfully carry out this mission is hampered

  • by the sheer number of products.

  • The FDA estimates there are more than 85,000 dietary supplement

  • products currently available in the U.S. alone.

  • So there's the sheer number, the under reporting of adverse

  • side effects, the difficulty of successfully prosecuting

  • cases against offenders, and the ease with which

  • suppliers can rebrand products removed from the shelves

  • have led to a largely unregulated environment.

  • In the real world, there is little guarantee that a supplement

  • will even contain what is advertised on the packaging and

  • not contain unlisted ingredients, potentially leading to significant

  • harms, resulting in an estimated 23,000 ER visits every year.

  • Now, of course, prescription drugs don't just sicken but kill many more,

  • making them perhaps the third leading cause of death,

  • wiping out more than 100,000 Americans, but still,

  • the less death and disability, the better.

  • Dietary supplements are often adulterated

  • with undeclared pharmaceuticals, which could represent

  • an enormous risk to consumers, most often found in erectile dysfunction,

  • weight loss, diabetes, and high blood pressure supplements.

  • But wait a second. What about

  • supplement manufacturers who say they have independent,

  • third-party certification of purity?

  • There is a practice called "dry labbing," a dirty little secret

  • of the supplements industry, where quality assurance labs

  • just rubber stamp fake documents.

  • And if you think that's outrageous, check out the story of BMPEA.

  • A researcher at Harvard published a paper replicating prior research

  • from the FDA detecting a designer amphetamine-like stimulant,

  • beta-methylphenylethylamine,

  • in various U.S. supplements sold in the United States.

  • In response, one of the offenders, Hi-Tech Pharmaceuticals,

  • manufacturers of weight loss supplements like

  • Black Widow and Yellow Scorpion,

  • sued the Harvard researcher for libel, slander, and product

  • disparagement, originally to the tune of $200 million in damages.

  • This was all documented in a piece by STAT,

  • which is an excellent source of medical journalism

  • that I recommend.

  • The head of Hi-Tech openly admitted that he was

  • "hoping that we were able to silence this guy."

  • And while ultimately unsuccessful in court, Hi-Tech's lawsuit effectively

  • sent a warning to other researchers.

  • In fact, Hi-Tech's CEO is attributed as saying,

  • he "hope[s] that the long and costly legal battle will scare away

  • other academics from investigating the supplement industry."

"Supplement Regulation and Side Effects: Efforts to Suppress the Truth"

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Supplement Regulation and Side Effects: Efforts to Suppress the Truth

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    林宜悉 發佈於 2022 年 10 月 31 日
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