And why is your computer mouse lagging? And why is the Triangle Bob made out of hamburger meat?

為什麼你的滑鼠卡卡的？ 還有為什麼 Triangle Bob 是用漢堡肉做的？

Ooh... Okay. Okay. I know what I have to make a video on. Queue the intro!

哦～我懂了。我知道我該做什麼影片了。進入開場白！

Hey there! Welcome to Life Noggin!

嘿，你們好！歡迎來到 Life Noggin！

While they may look like any ordinary mushroom, magic mushrooms are very complex!

雖然它們可能看起來像任何普通的蘑菇，但迷幻蘑菇是非常複雜的！

They include about 180 mushroom species that contain the psychoactive chemical, psilocybin.  

它們有大約 180 種含有精神活性化學物質迷幻藥的蘑菇。

When ingested, psilocybin is converted by the body to psilocin,  

攝入後，迷幻蘑菇會被身體轉化為迷幻藥。

which causes hallucinogenic or psychedelic effects including changes in perception, mood, and thought.

這會導致致幻或迷幻效果，包括感知、情緒和思想的變化。

And could even be used to treat mental disorders.

它甚至可以用來治療精神疾病。

Depending on a variety of factors, including  the strength of the mushroom, amount consumed, and the person's size,

取決於多種因素，包括蘑菇的強度、食用量和人的體型，

the mind-altering effects can last anywhere from four to six hours.

改變心智的效果可以持續四到六個小時。

These chemicals have a similar molecular structure to serotonin,  

這些化學物質的分子結構與血清素相似。

which is used by your body to deliver messages between nerve cells.

血清素是被你的身體用來在神經細胞之間傳遞信息。

And plays a role in many important functions like mood, sleep, and digestion.

並在情緒、睡眠和消化等許多重要功能中發揮作用。

Because these are so similar, psilocin binds to the same receptors.

因為它們非常相似，脫磷酸裸蓋菇素與相同的受體結合。

But its the activation of one of these receptors in particular,  5-HT2A, that causes the trippy effect,  

但它激活了這些受體之一，特別是 5-HT2A，導致幻覺效應，

which can include a more open mind, an intense sensory experience, and hallucinations.

這可能包括更開放的思想、強烈的感官體驗和幻覺。

5-HT2A are widely found in the cortex, the area of the brain responsible for reasoning and rational thought.

5-HT2A 廣泛存在於大腦皮層中，是大腦中負責推理的區域。

And they themselves are associated with the regulation of mood, imagination, and perception.

而它們本身也與情緒、想象力和感知力的調節有關。

Some research has also found that psilocin affects another part of the brain called the default mode network,

一些研究還發現，脫磷酸裸蓋菇素會影響大腦的另一個部分，稱為預設模式網絡。

which becomes active when your mind wanders during introspection.

預設模式網絡是當你在走神，就會變得活躍的區域。

The scientists responsible for the study believe that psilocin interferes with the neural connections here,  

負責這項研究的科學家們相信脫磷酸裸蓋菇素干擾了這裡的神經連接，

forcing the brain to make new, unusual connections that result in a fragmented sense of self.

迫使大腦建立新的、不尋常的聯繫，從而導致自我意識支離破碎。

This rewiring of the brain is helping scientists treat mental health disorders that are marked by fixed patterns of thinking, like depression.

這種大腦的重朔正在幫助科學家治療以固定思維模式為特徵的精神疾病，如憂鬱症。

One clinical trial even found that psilocybin-assisted therapy can alleviate major depressive disorder symptoms, in some cases for at least a year.

一項臨床試驗甚至發現，脫磷酸裸蓋菇素輔助治療可以緩解重度憂鬱症症狀，在某些情況下至少可以緩解一年。

Scientists are also researching its effects on OCD, addiction, and end-of-life anxiety.

科學家們還在研究它對強迫症、成癮和臨終焦慮的影響。

Of course, this is all in a research setting and, like any drug taken recreationally,  

當然，這都是在研究環境下進行的，和任何娛樂性服用的藥物一樣，

magic mushrooms can pose a serious health risk and in some cases, be life-threatening.  

迷幻蘑菇可能會帶來嚴重的健康風險，在某些情況下甚至會危及生命。

If too much is taken you can overdose and experience vomiting, psychosis, seizures, and even end up in a coma.

如果服用過多，你可能會過量服用並出現嘔吐、精神病、癲癇發作，甚至最終陷入昏迷。

Or you could have a negative reaction known as a bad trip where you may see a really unpleasant hallucination or feel panic or fear.

或者，你可能會出現一種被稱壞體驗的負面反應，可能會看到非常不愉快的幻覺，或者感到恐慌或恐懼。

People who don't have a support system around them can find themselves in a pretty dangerous and scary situation.

周圍沒有可以尋求幫助的人會發現自己處於非常危險和可怕的境地。

So please act responsibly and leave the  mind-altering medications and substances to professionals.

所以請負責任地行事，並將改變心智的藥物和物質留給專業人士。

You don't want to risk having those issues I previously mentioned.

你可不想冒險遇到我之前提到的那些問題。

You also don't want to risk getting misidentified poisonous ones or any mushrooms laced with something really bad!

你也不會想冒險誤認有毒的或任何帶有非常糟糕的東西的蘑菇！

So are there any other drugs you'd like me to discuss?

那麼，接下來你還有什麼其他藥物需要我討論嗎？

This was a highly requested video, so thank you to everyone who suggested it! I hope you actually learned something here!

這是大家一直敲碗的影片，所以，感謝每一位提出建議的人! 我希望你們真的有學到了一些東西！

Click here to watch this video we did on derealization or click here to watch this video!

點擊這裡觀看我們做的這個關於人格解體障礙的影片，或者點擊這裡觀看這個影片！

Don't forget to subscribe and click the bell so you're notified every time we upload a new video.

別忘了訂閱並開啟小鈴鐺，這樣我們每次上傳新的影片都會通知你。

And click the like button  because it really helps us out!

並按讚，因為這真的對我們有幫助！

As always, my name is Blocko, this has been Life Noggin. Don't forget to keep on thinking!

像往常一樣，我的名字是 Blocko，這裡是 Life Noggin，不要忘記繼續思考！