Yeah, and... I mean obviously, like, if you wanted to be really dramatic, you could say, 'Ah, what a... Woe is me!' or something like this, when you've lost your keys, but normally we say something like you 'add to somebody's woes'.
對,不過顯然如果你想要浮誇一點,你當然也可以在例如忘記帶鑰匙之類的時候,說「啊,這對我來說... 真是個大麻煩 (woe)!」,但我們比較常會用「給某人帶來大麻煩 (add to somebody's woes)」這種用法。