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  • [Gasps] -Thank you! I made it myself.

    [喘氣] -謝謝!我自己做的。

  • -Did you? -And it has microbes on it!

    -你有嗎?-而且上面有微生物!

  • -Oh look at them, they're so cute.

    -哦,看看他們,他們是如此可愛。

  • -I know! I like to think about which one's my favorite.

    -我知道!我喜歡思考哪個是我的最愛。

  • I think it might be this one.

    我想可能是這個。

  • At this very moment, there are trillions of microbes in and on your body. These bacteria, fungi,

    此時此刻,你的身體裡和身上有數萬億的微生物。這些細菌、真菌。

  • viruses and more are a part of our bodies from the moment we're born, and we need

    病毒等從我們出生的那一刻起就是我們身體的一部分,我們需要

  • them. The bacteria in our gut help us digest our

    他們。我們腸道中的細菌幫助我們消化我們的

  • food. The bacteria in our mouth and nose help us fight off infections.

    食物。我們口腔和鼻子中的細菌幫助我們抵禦感染。

  • Almost every part of your body has its own unique microbiome, or community of microorganisms,

    你身體的每個部分幾乎都有自己獨特的微生物群,或微生物群落。

  • and that includes...the vagina. And that's what I'm studying as a graduate

    而這包括......陰部。而這正是我作為一名研究所學生正在研究的問題。

  • student right now! Someone should really count the

    學生,現在!真的應該有人統計一下

  • number of times we say 'vagina' in this video because it's gonna be...a lot.

    我們在這段視頻中說 "陰道 "的次數,因為這將是......很多。

  • -I think one of the biggest misconceptions

    -我認為最大的誤解之一是

  • about the vaginal microbiome is that it's bad.

    關於陰道微生物組的說法是,它很糟糕。

  • A lot of people immediately will think that microbes are not helpful to us, when in fact,

    很多人立即會認為微生物對我們沒有幫助,而事實上。

  • the vaginal microbiome is incredibly important for protecting us from invading microbes that

    陰道微生物組對於保護我們不受入侵的微生物影響是非常重要的。

  • are bad. -There's an incredibly diverse microbial

    是壞的。-有一個令人難以置信的多樣化的微生物

  • party in there, and the party goers who take up the most space are a kind of bacteria called

    在那裡舉行的聚會,佔用空間最大的是一種叫做 "細菌 "的細菌。

  • lactobacilli. There are a bunch of different species in

    乳酸菌。有一堆不同的物種在

  • this group, but they all have a very important jobtaking up space and keeping the place

    這個小組,但他們都有一個非常重要的工作--佔用空間並保持這個地方。

  • acidic. These lactobacilli are producing lactic acid

    酸性的。這些乳酸菌正在產生乳酸

  • as they live their little lives, making your vagina have a pretty low pH.

    因為它們過著自己的小日子,使你的陰道有一個相當低的pH值。

  • This acidity is a really GOOD thing because it keeps the healthy bacteria happy, and it makes it

    這種酸度是一件非常好的事情,因為它使健康的細菌保持快樂,並使其

  • harder for bad bacteria to take over. This is also actually why you may notice stains

    壞細菌更難佔領。這實際上也是你可能注意到汙漬的原因

  • or bleached areas on your underwear even after washing them

    即使在清洗後,內衣上仍有漂白的地方---。

  • That natural acidity of your vaginal discharge is bleaching the pigment out of the fabric, and that's

    你的陰道分泌物的自然酸度正在漂白織物中的色素,而這就是

  • totally normal and fine. I promise you're not weird.

    完全正常,很好。我保證你不奇怪。

  • In fact, this might explode your brain, but the vagina's healthy acidity has been shown

    事實上,這可能會讓你的大腦爆炸,但陰道的健康酸度已被證明是

  • to decrease your risk of catching certain STIs, even lowering the likelihood of HIV

    降低你感染某些性傳播疾病的風險,甚至降低感染艾滋病毒的可能性。

  • transmission. Althoughusing a barrier like a condom or

    傳播。儘管--使用像安全套或其他的障礙物

  • a dental dam is still absolutely necessary if you want to minimize your STI risk as much

    如果你想盡可能地減少STI的風險,戴上牙罩仍然是絕對必要的。

  • as possible.

    儘可能的。

  • So maintaining that healthy community of microbes

    是以,保持這種健康的微生物群落

  • and that acidic environment is really important.

    而這種酸性環境真的很重要。

  • -For instance, it's associated with things

    -例如,它與事物有關

  • like bacterial vaginosis, which affects 10% of women in the U.S. every single year recurrently.

    像細菌性陰道病,在美國每年有10%的婦女反覆受到影響。

  • -If you've ever had BV, you know the struggle. Normal vaginal discharge is a combination

    -如果你曾有過BV,你就知道這種掙扎。正常的陰道分泌物是一種組合

  • of cells, fun stuff your microbes are producing, the microbes themselves, and cervical mucus,

    的細胞,你的微生物正在產生的有趣的東西,微生物本身,和宮頸粘液。

  • and it will vary in texture, color, and amount throughout your cycle.

    而且在整個週期中,它的質地、顏色和數量都會有所不同。

  • Usually, discharge is clear or white, and doesn't have a bad smell. But if that microbiome

    通常情況下,分泌物是透明的或白色的,並且沒有不良氣味。但是,如果該微生物組

  • gets upset, like if something makes it more difficult for your lactobacilli to thrive...then

    如果有什麼東西使你的乳酸菌更難茁壯成長......那麼,你的乳酸菌就會被打亂。

  • other species of bacteria will start to move in and take over. Your discharge may change color, and

    其他種類的細菌將開始移入並接管。你的分泌物可能會改變顏色,並且

  • start to smell different, and this...is bacterial vaginosis.

    開始有不同的氣味,這......就是細菌性陰道病。

  • It's an imbalance of the natural bacteria that are always there in your vagina,

    這是一種天然細菌的不平衡,這些細菌一直存在於你的陰道中。

  • they're just...

    他們只是...

  • out of whack.

    錯亂了。

  • If you've experienced this, you're not alone because it's the most

    如果你有這樣的經歷,你並不孤單,因為這是最

  • common vaginal issue for those of us under 45.

    對於我們這些45歲以下的人來說,常見的陰道問題。

  • Something similar is happening when you get a yeast infection. If your natural ecosystem

    當你得到酵母菌感染時,類似的事情也在發生。如果你的自然生態系統

  • of protective bacteria has been disturbed, the yeast that naturally live in your vagina

    保護性細菌被擾亂,自然生活在你的陰道里的酵母也會被擾亂。

  • then decide 'hey, now's my moment, let's multiply'.

    然後決定'嘿,現在是我的時刻,讓我們乘勝追擊'。

  • The most frustrating thing is that if you take a medication for one of these problems,

    最令人沮喪的是,如果你為這些問題之一服藥。

  • like antibiotics to treat the BV, that same medication increases your chance of developing

    如用抗生素治療BV,同樣的藥物會增加你患BV的機會。

  • another imbalance-driven issue, like a yeast infection.

    另一個失衡驅動的問題,如酵母菌感染。

  • It's like, can we catch a break? We have got to find other options than just

    這就像,我們能不能喘口氣?我們必須找到其他選擇,而不僅僅是

  • throwing antimicrobials at the problem.

    把抗菌劑扔給這個問題。

  • Actually, pro-tip, maybe you can ask your doctor a for probiotic

    實際上,建議你可以向你的醫生索取益生菌。

  • along with traditional antibiotic treatment for BV.

    與傳統的抗生素治療BV一起使用。

  • There's also some research that using an antifungal WITH an antibiotic at the treatment

    還有一些研究表明,在治療過程中使用抗真菌劑和抗生素,會使病情惡化。

  • stage can help prevent this odious self-reinforcing cycle...but we still need to find better solutions.

    舞臺可以幫助防止這種可憎的自我強化循環......但我們仍然需要找到更好的解決方案。

  • It's truly exhausting, because SO MANY things can upset your microbes: taking antibiotics,

    這確實很累人,因為有很多事情會擾亂你的微生物:服用抗生素。

  • being pregnant, having sex, getting your period, using menstrual products, being on birth control...Like

    懷孕、做愛、來月經、使用月經產品、採取避孕措施......如

  • there's so much admin that comes with a vagina!

    有這麼多的管理是伴隨著陰道而來的!

  • But if there is one thing you take away from this video, please let it be this: you don't

    但是,如果你從這段視頻中得到一件事,請讓它成為:你不

  • need to wash out your vagina. I know the world might have made you feel

    需要洗掉你的陰道。我知道這個世界可能已經讓你感到

  • like you are bad or dirty for producing discharge or for smelling how you smell but if you do

    就像你是壞的或骯髒的,因為你產生了分泌物或聞到了你的氣味,但如果你做了

  • something like douche, you are literally washing away all the good microbes that keep you safe

    像沖洗一樣的東西,你實際上是在洗掉所有保證你安全的好微生物。

  • and healthy. You never have to wash out your vagina. It

    和健康。你永遠不需要清洗你的陰部。它

  • cleans itself. And I know I get really worked up about this

    潔身自好。我知道我對這個問題非常著急

  • stuff, but that's because this microbiome business has way bigger impacts than just

    但是,這是因為微生物組業務的影響遠遠大於僅僅是

  • stuff like yeast infections, although they do suck.

    酵母菌感染之類的東西,儘管它們確實很糟糕。

  • -The vaginal microbiome is also implicated in secondary conditions. These include things

    -陰道微生物組也牽涉到繼發性疾病。這些情況包括

  • like preterm birth, STI acquisition, and even fertility.

    如早產、性傳播感染的獲得,甚至是生育能力。

  • -Yeah. That disruption of the natural vaginal microbiome, like we see with a condition like

    -是的。自然的陰道微生物組的破壞,就像我們看到的像這樣的情況一樣

  • BV, may increase your risk of developing pelvic inflammatory disease, a condition that can

    BV,可能會增加你患盆腔炎的風險,這種疾病可能會

  • lead to infertility if left untreated. Microbiome imbalance can increase your risk

    如果不加以治療,會導致不孕不育。微生物組的不平衡會增加你的風險

  • of getting HPV...and that's a big deal, because some types of HPV can lead to cancer.

    感染HPV......這是個大問題,因為某些類型的HPV可能導致癌症。

  • BV during pregnancy is associated with higher risk of premature birth, which poses all kinds

    懷孕期間的BV與較高的早產風險有關,這帶來了各種

  • of risks to both birthing person and baby. We need a better understanding of these microbial

    對分娩者和嬰兒都有風險。 我們需要更好地瞭解這些微生物。

  • dynamics so we can stop this from happeningthis is actually what I'm doing my master's

    動態,所以我們可以阻止這種情況的發生......這實際上是我正在攻讀碩士學位的內容。

  • thesis research on right now.

    現在就進行論文研究。

  • And all of that doesn't even BEGIN to get

    而這一切甚至還沒有開始得到

  • into stuff like urinary tract infections, which 50-60% of women will experience in their

    諸如尿路感染,50-60%的婦女在其一生中都會經歷這種情況。

  • lifetime. The vaginal and vulval microbiome definitely

    終身。陰道和外陰部的微生物組肯定是

  • affect conditions like UTIs, which also have long-term health implications, and don't

    影響尿毒症等情況,這也有長期的健康影響,並且不

  • have great solutions.

    有很好的解決方案。

  • Now, at this point, like me, you may be really frustrated

    現在,在這一點上,像我一樣,你可能真的感到沮喪了

  • by the lack of deep understanding and effective solutions we have for issues like this, but

    我們對這樣的問題缺乏深刻的理解和有效的解決方案,但

  • that is changing. And this is where companies like Hana's come in.

    這一點正在發生變化。而這正是像Hana公司這樣的公司出現的地方。

  • -We founded Juno Bio for two reasons. One is

    -我們創立朱諾生物有兩個原因。其一是

  • that we believe that we needed to close the gender health gap as quickly as we could,

    我們相信,我們需要儘快縮小性別健康差距。

  • and that this was one of the best ways of decoding the vaginal microbiome. The second

    並認為這是解碼陰道微生物組的最佳方法之一。第二項

  • reason is that to really decode the vaginal microbiome, we need data at scale and traditional

    原因是,要真正解碼陰道微生物組,我們需要大規模的數據,而傳統的

  • academic studies and the way that they're funded and run, just don't provide that scale.

    學術研究和它們的資助和運行方式,只是沒有提供這種規模。

  • Through the Juno study, we've built one of the world's richest and most representative

    通過朱諾研究,我們已經建立了世界上最豐富和最具代表性的

  • repositories of the vaginal microbiome.

    陰道微生物組的儲存庫。

  • -Because yeswe do see differences in microbiome

    -因為是的-我們確實看到了微生物組的差異

  • makeup across ethnicities and geographic areas, across different kinds of diets, and between

    不同種族和地理區域、不同種類的飲食以及不同年齡段的人之間的構成。

  • vaginas and neovaginasor vaginas that have been surgically constructed. ​

    陰道和新陰道--或經過手術建造的陰道。

  • So companies like Juno Bio and research teams all over the worldlike the one I'm working

    是以,像朱諾生物這樣的公司和世界各地的研究團隊--就像我正在工作的那個團隊一樣

  • withare trying to dig deeper and generate more data about the vaginal microbiome.

    他們正試圖更深入地挖掘併產生更多關於陰道微生物組的數據。

  • This will let us understand how these invisible creatures work, so that people with vaginas

    這將讓我們瞭解這些無形的生物是如何工作的,從而使有陰道的人

  • don't have to put up with conditions that the world treats as insignificant,

    不需要忍受被世界視為無足輕重的條件。

  • but that as we've seenactually have an oversized effect on our overall health.

    但正如我們所看到的,這實際上對我們的整體健康有很大的影響。

  • This research could lead to exciting developments like standardization of probiotics as complimentary

    這項研究可能會帶來令人興奮的發展,如益生菌的標準化,作為免費的補充。

  • therapy for BV; Better, more accurate screening tools to identify those at risk for preterm

    更好、更準確的篩查工具,以確定有早產風險的人。

  • birth; and... -vaginal microbiome transplants. So in 2019,

    生;以及...-陰道微生物組的移植。所以在2019年。

  • we had the first ever paper that showed that actually, if you take a vaginal microbiome

    我們有史以來第一篇論文表明,實際上,如果你採取陰道微生物組

  • sample from a healthy woman, and place it into a woman who's dysbiotic, you can actually

    將一個健康婦女的樣本放入一個有益生菌障礙的婦女體內,你實際上可以

  • cure things like intractable bacterial vaginosis.

    治療像頑固性細菌性陰道病。

  • Because it's not just about you. Your microbiome can affect

    因為它不只是關於你。 你的微生物組可以影響

  • the health of your sexual partners, and if you have a child, passing through the vaginal

    你的性伴侶的健康,如果你有一個孩子,通過陰道的

  • canal is that baby's introduction to its microbial world,

    運河是嬰兒對其微生物世界的介紹。

  • setting up its microbiome maybe for life. But you can see just how many different lives

    設置其微生物組也許是為了生活。但你可以看到有多少不同的生命

  • and fields are impacted by and involved in this aspect of female-bodied health.

    在女性身體健康的這個方面,有很多機構和領域受到影響並參與其中。

  • -We need a multidisciplinary approach and it's super important to have

    -我們需要一種多學科的方法,並且擁有超級重要的

  • scientists, clinicians, and the women that experience the conditions

    科學家、臨床醫生和經歷這些情況的婦女

  • associated with them all involved in decoding the vaginal microbiome.

    與他們相關的都是參與解碼陰道微生物組的人。

  • And the impact that it has on our health.

    以及它對我們的健康產生的影響。

  • -I feel really lucky to have found my niche in this fascinating field

    -我感到非常幸運,在這個迷人的領域找到了自己的定位

  • and I'm hoping to go on to do a PhD in exactly this.

    我希望能在這方面繼續攻讀博士學位。

  • So if you have questions, I hope to be part of finding the answers for all of us.

    是以,如果你有問題,我希望能成為為我們所有人找到答案的一部分。

  • But for now, let me leave you with

    但現在,讓我留給你的是

  • this. The best part about your vagina is that it's

    這一點。你的陰道最好的部分是它

  • really good at keeping you healthy, if you let it.

    如果你允許的話,它真的能讓你保持健康。

  • Say it with me: no scented products, no soap, no douching.

    和我一起說:不使用有香味的產品,不使用肥皂,不進行沖洗。

  • Just let it do its normal thing, and get in touch with what that normal is for you.

    就讓它做它正常的事情,並接觸到對你來說正常是什麼。

  • Thanks so much for watching Seeker's new series Body Language. I hope you've enjoyed this

    非常感謝您觀看Seeker的新系列《身體語言》。我希望你喜歡這個

  • video. And if there's another women's health topic you want us to cover,

    視頻。如果你有其他的女性健康話題希望我們報道。

  • leave us a comment.

    請給我們留言。

  • I'll see you next time!

    下一次見!

[Gasps] -Thank you! I made it myself.

[喘氣] -謝謝!我自己做的。

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