Name: 为什么中国考虑混合使用 Covid-19 疫苗（Why China Is Considering Mixing Covid-19 Vaccines | WSJ）
Uploaded: 2021-05-30T07:38:00.000Z
Duration: 4 min 20 s
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- [Narrator] Chinese COVID-19 vaccines are being used

among globally used coronavirus vaccines,

Compare this with shots from Pfizer-BioNTech, Moderna

The head of China CDC in early April said the efficacy

And this also included ones from his own country.

So China is looking to bolster the protection rate

and one way is to mix and match different types of vaccines.

that would look at mix and match regimens.

- [Narrator] Spain is also interested in combining vaccines

to overcoming multiple vaccination challenges at once.

Most Chinese vaccines and other shots currently in use

require two doses, creating an opportunity to mix and match.

Some immunologists believe this could have a number

of benefits like boosting the immune response.

- The theory is that if you train the immune system

to recognize a virus in a slightly different way each time,

- [Narrator] And a more robust immune response

is important since China has confirmed cases

that were first identified in the UK and South Africa.

Mixing and matching for this reason has gotten support

from at least one Chinese drug maker so far.

that mixing and matching could ease the pressure

in countries that are rolling out Chinese vaccines

using two different shots could give doctors more options

when patients come in for the second dose.

or severe allergic reaction to the first shot that they get,

by giving them the second dose from a different vaccine.

- [Narrator] The idea became particularly important

health authorities are advising younger people

who have received a first dose of AstraZeneca

to get a second dose of a different vaccine.

The drug maker said it's working with health regulators

and starting the rare blood clotting events

While these upsides could bring China and other countries

closer to getting their population vaccinated,

health authority say there's still a lot to learn

about possible side effects or how it may affect efficacy

of the vaccines, especially when it comes

to combining shots made with different technologies.

and the vaccines by AstraZeneca and Johnson & Johnson

are vaccines that use a virus as the vector

to get the genetic instructions into your body.

- [Narrator] Whereas Pfizer-BioNTech and Moderna vaccines

use a new gene-base technology involving messenger RNA,

where molecules carry genetic instructions.

when you mix these two technologies together.

- [Narrator] Chinese health authorities have said people

can receive different brands that use the same technology,

of two homegrown vaccines with different technologies

are underway in China with more than a hundred volunteers.

The country is also working on its own mRNA vaccine

and looking closely at approving Pfizer-BioNTech shot,

according to people familiar with the matter.

This would pave the way for China to mix and match

its more conventional vaccines with mRNA shots.

Similar to how researchers in the UK are studying

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为什么中国考虑混合使用 Covid-19 疫苗（Why China Is Considering Mixing Covid-19 Vaccines | WSJ）

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