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  • oh yes yes i'm vaccinated  yes  

  • Very cool

  • yes

  • yeah

  • yes, I did

  • it was very cool to to know  

  • okay I'm gonna be vaccinated withvaccine that I know really from day one

  • I mean who can tell that they're part of  the solution for such a pandemic situation  

  • I guess only a few people can say that and  I'm really happy to be part of that

  • If you've been vaccinated for COVID-19, chances  are that you are benefiting from the science  

  • happening here at the German biotech company  BioNtech.

  • In December 2020 BioNtech in partnership with Pfizer

  • were the first to earn authorization  to distribute their vaccine to the public

  • In March 2021 TIME spent  a week watching how BioNtech makes a batch  

  • of 8 million doses of the COVID-19 vaccine  at their new manufacturing plant in Marburg  

  • they expect to produce 1 billion doses a year

  • the pace of production has been breakneck from the start  

  • So in 2020 I think we worked 

  • at every holiday, I can remember Easter  Saturday I was standing here pipetting  

  • samples to have the results as soon as possible 

  • and now 24-hour shifts in this lab are producing  

  • vaccines that will be shipped around the  world

  • There are approximately 50, 000 steps at the lab  

  • it begins with bags of pure mRNA the molecule  that tells cells how to make the proteins that  

  • launch the immune response and a buffer  solution that starts the coding process  

  • it emerges in bulk at the other end of  the process as a liquid destined for vials

  • most of the machines are named after  the engineers that developed the process  

  • this one is named after Margaret the first patient  in the clinical trials to receive the vaccine  

  • but the beating heart of the lab is this machinecontainer that uses pressurized ethanol to encase  

  • the mRNA and special lipid nanoparticles

  • those nanoparticles keep the mRNA protected until it  

  • can jumpstart the immune response in the  body's cells

  • Speed is essential but inside the lab  everyone moves slowly and methodically 

  • each of the 50,000 steps is logged by one technician confirmed  by a second and only then does it actually happen  

  • it's very important that the quality of the  product and all the raw materials is perfect  

  • here and so no impurities should be present  in all raw materials and nothing which we don't  

  • want to have in our products

  • one wrong move has the potential to damage the final product  

  • if there's any accidental exposure  let's say from an ill-timed sneeze  

  • the entire batch must be thrown out, all eight  million doses that's why everyone wears layers  

  • of protection and they even disinfect their  gloved hands repeatedly

  • in the lab where we were filming no one had ever told  the technicians how many doses were in a batch  

  • after that they sprayed another application of  disinfectant onto their gloves just to be sure

  • based on our technology and on  the antigen we were using no I wasn't

  • I'm very confident in the technology we have

  • until now vaccine development has been a slow process  

  • the BioNtech vaccine uses a new technology  based on mRNA it is revolutionizing the way  

  • vaccines can be produced

  • When the COVID-19 pandemic broke out, BioNtech was primarily a cancer vaccine company 

  • but by using this new mRNA technology it was able  

  • to quickly pivot to a coronavirus vaccine

  • when you look back at any project you've ever done you've  

  • always looked back at the start and go wow okay if  I'd known that now i could have cut you know a few  

  • hurdles out of my way earlier right but you're  in a situation where you're doing something  

  • especially for us as a smaller company that was  unprecedented

  • the second part of the process happens at another factory

  • where vials are filled  and packed into boxes for shipment

  • as the cycle  comes to an end there's little time to celebrate  after all another batch is waiting to be made  

oh yes yes i'm vaccinated  yes  

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B2 中高級 美國腔

製作COVID-19疫苗:50,000個步驟(Making the COVID-19 Vaccine: A 50,000 Step Process | TIME)

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    joey joey 發佈於 2021 年 05 月 27 日
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