without the distracting lights at the club

燈火闌珊

or the mood lighting of the bar,

或酒吧的氣氛照明。

we have noticed some peculiar things

我們注意到一些奇怪的事情

about our face as we drink.

在我們喝酒時，我們的臉。

- So we decided to do a little research,

- 所以我們決定做一下調查。

try a little experiment

試探

and figure out why and how alcohol changes your face.

並找出酒精改變你面容的原因和方法。

- Here are the rules of our experiment.

- 下面是我們的實驗規則。

We are going to drink for 12 hours.

我們要喝12小時。

One drink every hour.

每小時喝一杯。

That might not seem like a lot to some people

對有些人來說，這可能不是什麼大問題。

but we are for sure lightweights.

但我們肯定是輕量級的。

We will take photos of our face

我們會拍下我們的臉

every three hours during the day

三更半夜

as we drink and one tomorrow morning

當我們喝酒的時候，明天早上再喝一杯

to see how alcohol changes our faces.

來看看酒精是如何改變我們的臉。

We are going to copy our day from yesterday,

我們要複製昨天的一天。

the same amount of coffee, same two liters of water,

同樣的咖啡量，同樣的兩升水。

same veggie meals and snack,

同樣的素食餐和零食。

one half-hour workout, our nightly one hour walk

半小時的鍛鍊，我們每晚一小時的步行。

and we already took photos every three hours yesterday

我們昨天已經每隔三個小時拍一次照片了

to compare our sober photos

來比較我們的清醒照片

from then to the drunk ones we take today.

從那時到今天的醉翁之意不在酒。

Don't try this at home.

不要在家裡嘗試這個。

Oh, okay.

哦，好吧。

You're ready.

你準備好了

(foreign language)

(外文)

- [Mitch] Where'd you learn that?

- 你從哪裡學來的？

- I don't know.

- 我不知道。

I think I saw it once in a movie Ratatouille probably.

我想我可能在一部電影《料理鼠王》中看到過一次。

See you later, bud.

回頭見，夥計。

Oh.

哦。

- Okay.

- 好吧，我知道了

Yeah.

是啊。

Oh, from now on all

哦，從現在開始，所有的

of our drinks will be measured to be around the same amount.

我們的飲料會被測量到大約相同的數量。

So if we have a shot of liquor

所以，如果我們有一個鏡頭的酒

it'll be around 45 milliliters at 40% alcohol.

在40%的酒精濃度下，它將會是45毫升左右。

If we have a glass of wine,

如果我們有一杯酒。

it will be around 150 milliliters at 12%.

在12%的情況下，它將是150毫升左右。

And if we have beer or cider

如果我們有啤酒或蘋果酒

it'll be around 350 milliliters at 5% alcohol.

在5%的酒精濃度下，它將會是350毫升左右。

Cheers.

乾杯。

And I already have to pee.

而我已經要尿尿了。

See you in a minute.

一會兒見。

- According to my understanding of biological pathways

- 根據我對生物途徑的理解

it's probably not the alcohol, but I have to shit.

可能不是因為酒精，但我得拉屎。

- [Mitch] Ooh, drink number two.

- [米奇]哦，二號酒。

- We have got the good grapes

- 我們已經得到了好葡萄

from a local brewery here in Toronto.

來自多倫多當地的一家啤酒廠。

- [Mitch] Ooh look at these glasses.

- [米奇]哦，看看這些眼鏡。

- We got a Mariah Carey.

- 我們得到了一個瑪麗亞-凱莉。

Then we got a Charles Darwin,

然後我們得到了一個查爾斯-達爾文。

who we're also gonna fill up

我們也將填補誰

'cause Charles Darwin, as we all know was the bottom.

因為查爾斯-達爾文，我們都知道是最底層的人。

- This is the first time I'm having a beer type thing

- 這是我第一次喝啤酒類型的東西。

before noon.

中午之前。

With many more drinks to come,

還會有更多的酒。

we thought it would be fun to try

我們認為這將是有趣的嘗試

and explain the science of alcohol

釋酒

or getting progressively more drunk through the day.

或通過一天的時間逐漸醉倒。

- Now you know how we make our videos.

- 現在你知道我們如何製作視頻了吧。

So what is happening in your body right now?

那麼現在你的身體發生了什麼？

Alcohol is absorbed into your bloodstream

酒精會被吸收到血液中

through the GI tract and starts getting absorbed

通過胃腸道並開始被吸收。

in your stomach, which is why it can hit so fast.

在你的肚子裡，這就是為什麼它能如此迅速地擊中。

The alcohol molecule then moves through your blood

酒精分子就會在你的血液中移動。

to the brain and central nervous system

大腦和中樞神經系統

and changes how your neurons or brain cells communicate.

並改變你的神經元或腦細胞的交流方式。

You have two important neurotransmitters in the body.

你體內有兩種重要的神經遞質。

Glutamate, which affects excitatory neurons

穀氨酸，影響興奮性神經元。

and GABA, which affects inhibitory neurons.

和GABA，影響抑制性神經元。

It turns out alcohol suppresses the excitatory

原來，酒精能抑制興奮性的

neurotransmitter glutamate,

神經遞質穀氨酸。

and increases the inhibitory neurotransmitter GABA,

並增加抑制性神經遞質GABA。

which causes information flow to become slow,

導致資訊流動變得緩慢。

causing you to feel less, perceive less, notice less

導致你感覺不到，感知不到，注意不到

and remember less.

並少記。

The increased GABA hushes the background noise of activity,

增加的GABA使活動的背景噪音安靜下來。

clarifying your thoughts to an excessive degree.

澄清你的思想，以過度的程度。

You think less with great clarity.

你想得少了，很清楚。

Hence you're like this dog is amazing.

是以你會覺得這隻狗很神奇。

Essentially alcohol makes you think clearly about nothing.

本質上酒精讓你什麼都想不清楚。

- Guess what?

- 你猜怎麼著？

I have to pee.

我得去尿尿

- I haven't peed yet.

- 我還沒尿過呢

I'm sick or are you sick?

我有病還是你有病？

- I wanna know your most iconic drunk story.

- 我想知道你最經典的醉酒故事。

- I was drunk a lot in my youth.

- 我年輕時喝了不少酒。

I was in university,

我在大學裡。

I learned the bad romance dance.

我學會了糟糕的浪漫舞蹈。

You know the part, which she goes on the floor

你知道她趴在地板上的那部分吧

and she puts her leg up.

她把她的腿。

Oh my God, whole bar watching me leg up everything.

哦，我的上帝，整個酒吧看我腿了一切。

But I also was a university student,

但我也是一名大學生。

didn't have very much money.

沒有太多的錢。

I had the same emo tight black pants,

我也有同樣的情趣緊身黑褲。

with a huge rip in the crotch.

襠部有一個巨大的撕裂。

As I lift my leg up, my balls fall out.

當我把腿抬起來的時候，我的球就掉了出來。

Like hold mid Lady Gaga dance routine out of the bar.

就像抱著中間Lady Gaga的舞蹈表演出了酒吧。

Yeah I got kicked out for my balls

是啊，我被踢出了我的球

falling out on a dance floor.

在舞池中摔倒。

- I have to pee.

- 我得去尿尿

- [Greg] Time for the first photo.

- 第一張照片的時間到了

Do you feel like your face is different?

你是否覺得自己的臉不一樣了？

- Um no, I actually feel like it's harder

- 嗯，不，其實我覺得更難了

not to smile right now.

不笑現在。

While the first few drinks were fun,

雖然前幾杯酒很有趣。

things started to unravel.

事情開始變得撲朔迷離。

What just happened?

剛才發生了什麼？

Tell everyone.

告訴大家。

- I forgot I had therapy.

- 我忘了我有治療。

(both laughing)

（兩個笑）

- I am starting to feel sick.

- 我開始覺得不舒服了。

My body is, my brain's still having fun

我的身體是這樣，我的大腦還在享受著樂趣。

but my body is starting to feel not so great.

但我的身體開始感覺不是很好。

And we're only halfway through.

而我們才走了一半。

- Ugh I hate this.

- 呃，我討厭這個。

- I can literally feel my hangover starting.

- 我真的可以感覺到我的宿醉開始了。

Gotta pee BRB.

我得去尿尿BRB。

- [Mitch] What are you doing?

- [米奇]你在做什麼？

- I'm looking at TikTok aren't we all?

- 我在看TikTok，不是嗎？

- [Mitch] Yes, you're turning red.

- 是的，你變紅了。

It's happening, the flush.

它的發生，沖洗。

Greg's classic red face meant it was time

格雷格的經典紅臉意味著是時候了

for some more drunk science.

對於一些更醉的科學。

- [Greg] Three, two, one go.

- 三，二，一開始。

- Now the reason I may be feeling a little bit sick

- 現在，我可能會覺得有點不舒服的原因。

and Greg may have a bit of a red face is

而格雷格可能有一個有點紅的臉是

because of complex biochemistry in our bodies.

因為我們體內複雜的生物化學。

Alcohol is processed in the liver where enzymes

酒精在肝臟中被處理，其中酶的作用是讓酒精進入肝臟。

break down the alcohol into acetaldehyde.

將酒精分解為乙醛。

Acetaldehyde is 10 to 30 times more toxic

乙醛的毒性為10至30倍。

than alcohol leading to the headaches

比酒精導致的頭痛

and nausea we feel while drinking.

以及我們在喝酒時的噁心感。

In order to get rid of, and excrete the alcohol byproduct

為了擺脫和排洩酒精副產品。

of acetaldehyde,

或乙醛。

it needs to be converted to acetate by glutathione

它需要通過谷胱甘肽轉化為乙酸酯。

of which there's only a finite amount.

其中只有有限的數量。

East Asian people have a gene variant that leads

東亞人有一種基因變異，會導致

to higher levels of acetol aldehyde

對較高含量的乙醛的影響。

causing increased sickness and potential for red face.

導致病症增加，有可能出現紅臉。

Greg's not East Asian, obviously

很明顯，Greg不是東亞人

and likely his right face is for a different reason.

而且很可能他的右臉是出於另一個原因。

Studies have found that British, Irish

研究發現，英國、愛爾蘭

and Indigenous Americans get alcohol redness

和土著美國人得到酒精紅

due to changes in metabolism of vasoactive amines

由於血管活性胺的代謝變化所致

such as histamines,

如組胺。

which cause vasodilation of blood vessels

血管擴張

in the face and can also lead to inflammation of the face.

在面部，也會導致面部發炎。

So we will see what happens

所以我們將拭目以待

to Greg's British ass face later on tonight

到格雷格的英國屁股的臉今晚稍後。

slash in the morning.

早上的斜線。

- Why did you just talk about my face there bro?

- 為什麼你剛才說我的臉，兄弟？

It was similar to what we had in India.

這和我們印度的情況差不多。

- Oh my God. - [Mitch] Okay.

- 哦，我的上帝。- [米奇]好的

Oh, it looked at your butt crack.

哦，它看著你的屁股縫。

- Wait really is my butt out?

- 等等真的是我的屁股出來了嗎？

- [Mitch] No.

- [Mitch] No.

- There's nothing more unattractive than a butt crack.

- 沒有什麼比屁股裂縫更難看的了。

- [Mitch] A little like hot pink like underwear though.

- [米奇]有點像熱粉色的內褲，雖然。

- Really?

- 真的嗎？

So we are here at Dosa.

所以我們在多沙。

If you're in Toronto, come here it's so amazing.

如果你在多倫多，就來這裡吧，這裡太神奇了。

I feel like I'm James Charles.

我覺得我是詹姆斯-查爾斯。

It is so amazing.

它是如此的神奇。

We ate here yesterday for dinner,

我們昨天在這裡吃了晚飯。

we're eating it again for dinner today.

我們今天晚餐又要吃它。

I am drunk and I honestly just love this restaurant

我喝多了，老實說，我就是喜歡這家餐廳。

and I want people to come here.

我希望人們來這裡。

- Love Dosa.

- 愛上Dosa。

- We're at 11% alcohol.

- 我們在11%的酒精。

So I'm gonna go a bit over 150.

所以我要去150多一點。

If you are around, people have like classist ideologists,

如果你在身邊，人們都有喜歡的階級主義思想家。

they'll say it's skin contact natural wine.

他們會說這是皮膚接觸的天然酒。

I love wine that looks like a hangover piece.

我愛的酒，看起來像個宿醉的作品。

- It's six o'clock we've had nine drinks.

- 現在是六點，我們已經喝了九杯。

- Yeah, alcohol made out of potatoes.

- 是啊，用洋芋做的酒。

Potatoes!

洋芋！

Do you have agua congas?

你有水聰嗎？

Congas.

康加斯。

- You ready to have a sip or do I have a suck?

- 你準備好喝一口還是我吸一口？

- Hang on girl.

- 等一下，女孩。

It's your life, I'm just living in it.

這是你的生活，我只是活在其中。

- [Mitch] At this point, things got a bit weird.

- 這時候，事情變得有點奇怪了

We're just gonna leave this here.

我們只是要去離開這裡。

(upbeat music)

(歡快的音樂)

(slow music)

（慢音樂）

(rock music)

(搖滾樂)

(upbeat music)

(歡快的音樂)

(rock music)

(搖滾樂)

Yeah, we decided to do one final drunk science

是啊，我們決定做最後一次醉酒的科學。

on why alcohol makes you pee.

為什麼酒精會讓你撒尿。

- Is Bio chemistry 101.

- 是生物化學101。

- Part one is that I've just consumed so much liquid today.

- 一部分是我今天剛喝了那麼多液體。

But on top of that, there's another factor.

但除此之外，還有一個因素。

There's another factor. - Oh factor.

還有一個因素。- 哦，因素。

- Your kidneys. - They're really cute huh?

- 你的腎臟。- 他們真的很可愛，是吧？

- They're so cute.

- 他們是如此可愛。

Your kidneys is where your body decides to reabsorb water.

腎臟是你的身體決定重吸收水分的地方。

You are dehydrated is gonna to reabsorb more water

你缺水是要去重新吸收更多的水分的

so that you stay hydrated.

以便你保持水分充足。

Antidiuretic hormone goes to your kidney creates aquaporins.

抗利尿激素到你的腎臟創造水汽素。

And these aquaporins are proteins and they reabsorb water,

而這些水汽蛋白是蛋白質，它們會重新吸收水分。

from your kidneys back into your body.

從你的腎臟回到你的身體。

- So ultimately alcohol has an impact on ADH

- 所以最終酒精對ADH有影響

by decreasing it.

通過減少它。

(laughing)

（笑）

When you drink, your body doesn't have the same mechanism

當你喝酒的時候，你的身體沒有同樣的機制。

to save the water.

以節約用水。

- Yes.

- 是的，我知道

- And so it just goes through your body in and out.

- 所以它只是通過你的身體進進出出。

- And then you pee all potassium, UPF sugars.

- 然後你把鉀、UPF糖類都尿了。

- We will relate to tomorrow morning

- 我們明天早上再聯繫

when we are H-U-N-G over because-

當我們在H-U-N-G，因為 -

- I thought you were gonna lean over and say hung.

- 我以為你會靠過來說 "掛"。

And I'm going to say, "Oh boy!"

我想說，"哦，天哪！"

- Girl, that's all the time.

- 女孩，這是所有的時間。

- As we made it to the last few drinks,

- 當我們喝到最後幾杯的時候。

it got a little rough.

它得到了一個有點粗糙。

- Okay.

- 好吧，我知道了

It's become too much for me.

這對我來說太難了。

You hate alcohol?

你討厭酒精？

- Yeah, I think it makes me feel not aware of the world.

- 是啊，我覺得這讓我覺得不瞭解這個世界。

It makes me not feel present

它讓我感覺不到存在

and we only have like the years we're alive.

我們只有像年 我們還活著。

I don't want to spend it like this.

我不想這樣度過。

- I would not do this again.

- 我不會再這樣做了。

- No pictures.

- 沒有圖片。

- [Mitch] We're taking a photo now.

- [米奇]我們現在正在拍照

- TMZ no.

- TMZ不。

- [Mitch] Final photos captured.

- [米奇]最後的照片拍攝。

We went to bed bracing for the morning.

我們去睡覺了，為早上的事情做準備。

Of course we were so hung over we forgot

當然，我們喝多了，忘了

to vlog us taking our morning pictures.

來記錄我們拍攝我們的早晨照片。

- So here we are, a week later.

- 所以我們在這裡，一個星期後。

- It took us that long to recover from the hangover.

- 我們花了那麼長時間才從宿醉中恢復過來。

- We did not film our hangover 'cause it was disgusting

- 我們沒有拍下我們的宿醉，因為它是令人厭惡的。

and depressing.

和壓抑。

- I have not been that hung over in a long time

- 我已經很久沒有這麼宿醉了。

because we don't drink nearly as much anymore.

因為我們不喝幾乎一樣多了。

It hurt.

疼啊

We are now going to look at our comparison.

我們現在來看看我們的比較。

(laughing)

（笑）

- Oh my God.

- 哦，我的上帝。

- Okay.

- 好吧，我知道了

It is obviously so red, but it's not that bad.

明明是那麼紅，但也沒那麼差。

It's actually isn't that bad.

其實沒那麼糟。

- [Greg] Like I mean, it is for like any other person.

- 就像我的意思是，它是對任何其他人一樣。

- It's interesting that it happened presumably a lot

- 有意思的是，它發生了大概很多

at this point in the middle of our drinking

酒酣耳熱

or near the beginning.

或接近開始。