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  • Each and every person is walking around with a large community, up to 10 million,

  • bacteria both in and on our body.

  • If you want to think about that in terms of weight, your brain is probably around 6 pounds,

  • and you probably have at least that weight of bacteria in you and on you.

  • So it’s a significant amount of what we walk around with everyday.

  • This is uBiome in San Francisco, the first BioTech Company to be started with

  • a crowdfunding campaign.

  • Their big bet, that people will want to pay to find out what’s in their microbiomes,

  • kind of like people pay for DNA tests.

  • The microbiome is the community of microorganisms that live on us and in us.

  • They digest our food, they synthesis vitamins, they drug us with chemicals that

  • they make, they prevent us from getting diseases.

  • So they are as integral to our health and wellness as our own bodies.

  • This area of science is still very new, but uBiome has found enough interest to create

  • a line of products.

  • One for people who are simply curious who can take a basic test to find out more about

  • how their diet is affecting their gut, that’s called Explorer.

  • And then there is a more intense version that only a doctor can order for you, called SmartGut.

  • You can tell people medical information, you can involve their doctor, you can turn

  • what was interesting information about the microbiome into sort of hard medical data

  • that you can use to make medical decisions.

  • The kits range in cost.

  • From $89 to $399 depending on how many kinds of tests you want.

  • You can also get a subsidized test if your doctor prescribes it.

  • The kit comes in the mail.

  • You keep it in the bathroom so that when youre ready to give a sample it’s right there

  • with all the instructions.

  • You mail it back without ever having to go to a lab or the doctor.

  • But, let’s be clear, this is a little more intense than a DNA test.

  • The majority of samples that we receive come from the intestinal or the gut microbiome.

  • And in that case, a patient will take a sample of a small bit of stool from

  • their toilet paper.

  • So each of our robots is set up to do one or more specific tasks.

  • This one is extracting DNA from our samples.

  • So we have laid out 96 poo samples and were breaking down those samples and extracting

  • the genetic material.

  • Breaking down the poo.

  • Breaking down the poo.

  • When sequencing is complete, that sequence can go into a series of computer

  • programs that process the sample and we can then give a report back to our customers

  • that tell them about the bacteria in their sample.

  • uBiome has an argument for why this is an important test and potentially a better

  • business than genetic testing.

  • The company says that impowered by the information you may actually be able to change the makeup

  • of your gut by adjusting your diet.

  • It detects specific pathogens.

  • It helps people know which commensal bacteria they have in their gut and whether or not

  • it makes them more likely to have IBD versus IBS.

  • You can actually do something about it.

  • You can actually influence your own health and improve it and I see us having a really

  • big role in that ecosystem.

  • One of the things that having our tests allows us to do is so we can partner

  • with collaborators around the world to start to generate a lot more information around

  • how to interpret the microbiome.

  • We have over 150,000 samples in our data set now and we should have half a million

  • by the end of 2018.

  • Microbiome research is in its infancy but the uBiome founders think one day tests

  • like this will be just as common as blood tests, or maybe even more.

  • They think every time you have the flu or get food poisoning, every time you start a

  • new diet plan youll want one.

  • If theyre right, we might all have to get comfortable swabbing our toilet paper.

Each and every person is walking around with a large community, up to 10 million,

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腸道測序是健康檢測的未來嗎? (Is Gut Sequencing the Future of Health Testing?)

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    林宜悉 發佈於 2021 年 01 月 14 日
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