telomere
US /'teləˌmɪr/
・UK /'teləmɪə/
A1 初級
n.名詞端粒
Telomeres act as caps to keep the sticky ends of chromosomes from randomly clumping together
影片字幕
你其實不只一個年齡段 (You're Actually More Than One Age)
04:24
- One of them is telomere length.
其中一個是端粒長度。
- Understanding your rate of biological aging, epigenetic biological age, and telomere length
瞭解你的生物衰老率、表觀遺傳生物年齡和端粒長度
為何我們會老化？是否能停止老化，永垂不朽？ (How Long Will You Live?)
06:26
- So every time a cell divides, it loses some of the telomere. They estimate about 200 base pairs.
每當一個細胞分裂，它就會失去一些端粒子，經估算約有 200 對。
- So the telomere, and the telomere getting shorter is like your molecular clock. The cellular clock inside each cell that tells it how many times it has divided.
染色體逐漸變短，就像是你的分子時鐘，這個細胞時鐘告訴它已經分裂了多少次。
太神了！靜坐能改變大腦構造！？The Scientific Power of Meditation (The Scientific Power of Meditation)
03:03
- And a shortened telomere length has been linked to several diseases such as cardiovascular disease, diabetes, Alzheimer's, and cancer.
而縮短的端粒與某些疾病的產生息息相關，如心血管疾病、糖尿病、阿茲海默症以及癌症。
- Amazingly, when cancer survivors completed a meditation program, their bodies showed significant increases in telomere length.
驚人的是，當癌症病患完成一套冥想療程，他們體內的端粒長度有顯著增長。
人體在太空中會發生什麼？ (What Happens to the Human Body in Space?)
05:27
- from telomere shortening to gut microbiome changes to rapid alteration of gene expression.
從端粒縮短到腸道微生物組變化再到基因表達的快速改變。
適合 50 歲以上人群的唯一 8 種抗衰老運動！(醫生從不說） (The ONLY 8 Anti-Aging Exercises for Those Over 50! (Doctors Never Say))
19:48
- Studies show that regular walking can slow the rate of telomere shortening, the ends of chromosomes that are directly related to cellular aging.
研究表明，經常步行可以減緩端粒縮短的速度，端粒是染色體的末端，與細胞衰老直接相關。
為什麼女性的禁食方式與男性不同...... | 運動與營養科學家 Stacy Sims 博士 (Why women should FAST differently than men… | Exercise & Nutrition Scientist Dr Stacy Sims)
07:57
- And unfortunately, a lot of those times we look at clinical research and it gets transposed over to health and fitness without actually asking if it's viable. So then we look at the lower end of the fitness population. People are just learning to move and wanting to move. And like, I also want to lose more body fat so that I can move better. Oh, I'll start fasting. And when we see a lot of the like push on it, it comes from male data again. So when we start looking at women and a lot of women used to come with their partners to see me and say, I don't understand. We're both doing the same kind of fasted training. He's leaning up and getting fitter. I'm putting weight on and getting slower. I'm like, okay, well we have to separate it out, right? If you're a woman, you want to fast for all the health reasons that we hear about with regards to telomere length, improving longevity, improving our body's metabolic control. Then we work with our circadian rhythm where we stop eating at dinner. So we have dinner and we don't eat two to three hours before bed.
不幸的是，很多時候我們看臨床研究，並將其移植到健康和健身領域，而沒有真正問及它是否可行。是以，我們關注的是低端健身人群。人們剛剛學會運動，想要運動。比如，我也想減掉更多的體脂，這樣我就能動得更好了。哦，那我就開始禁食。當我們看到很多類似的推動力時，它又來自男性數據。所以，當我們開始關注女性時，很多女性會和她們的伴侶一起來找我，然後說，我不明白。我們都在做同樣的快速訓練。他越來越瘦，身體越來越好。我體重增加，速度變慢。我就想，好吧，我們得分開來，對吧？如果你是女性，你想禁食的所有健康原因我們都聽說過，如端粒
55 歲單親媽媽的逆齡生活 (Meet The 55 Year Old Single Mom Who's Aging Backwards)
18:02
- This is the part that really sold her on this specific supplement is that when she took the telomere test where she got the really good score, she was going through a really, really stressful time and she was off all of her habits.
讓她對這種特殊保健品產生興趣的原因是，當她在端粒測試中取得非常好的成績時，她正在經歷一段非常非常緊張的時期，而且她已經戒掉了所有的生活習慣。
端粒酶的功能 - 動畫 (Telomerase Function - Animation)
02:09
- The repeat unit shown here is from Tetrahymena, which is the model organism used in telomere and telomerase research. The DNA polymerase function of telomerase then synthesizes a DNA strand complementary to the RNA found in the telomerase and subsequently translocates to the end of the newly synthesized strand, and the process repeats itself.
這裡顯示的重複單元來自四膜蟲，四膜蟲是端粒和端粒酶研究中使用的模式生物。 端粒酶的DNA聚合酶功能會合成一條與端粒酶中的RNA互補的DNA鏈，然後轉位到新合成鏈的末端，這個過程會不斷重複。
癌症可能終於遇到了它的對手! (Cancer May Have Finally Met Its Match!)
04:09
- turn into cancer, but there are ways to lengthen the telomere. The main way is with an enzyme
變成癌症，但是有一些方法可以延長端粒。主要的方法是用一種酶
我們必須變老和死嗎? (Do We Have to Get Old and Die?)
02:58
- since these lost bits come from the telomere end caps that don't encode important information.
因為這些失去的部分是從不會編碼資訊的端粒的保護套。
- Age-defying species like naked mole rats, however, pump out high levels of a telomere-rebuilding enzyme that enables them to keep on replacing old and dysfunctional cells indefinitely.
然而，抗衰老種類如裸鼴鼠，生產高度的重建端粒酶持續地取代舊的和不正常的細胞。