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  • - [Narrator] Humans need dentists. It's a fact.

    〔旁白〕人類需要牙醫,這是無法抹滅的事實。

  • In 2017 alone,

    單單 2017 年,

  • Americans spent $129 billion on dental visits,

    美國人便花費 1 千 2 百 90 億美元看牙醫,

  • and an estimated 90% of adults in the US have fillings.

    而且約有 90% 美國成年人有補牙。

  • But many animals don't have this problem

    然而,許多動物卻沒有這樣的問題,

  • because they can regrow their teeth,

    因為牠們的牙齒可以重新生長,

  • replacing old damaged ones with brand new pearly whites.

    以新生的珍白牙齒取代受損的老舊牙齒。

  • Wouldn't it be great if you could do that?

    如果人類的牙齒也有這功能,那不是很棒嗎?

  • Well, there's actually an important trade-off

    這樣的麻煩其實隱含著

  • for this nuisance.

    重要的取捨。

  • Only a handful of mammals can regrow teeth multiple times

    相較於 5 萬種爬蟲類和魚類,

  • compared to the 50,000 species of reptiles and fish.

    僅有少數哺乳類動物可以多次重新生牙。

  • Take geckos for example.

    好比說壁虎,

  • They replace all 100 or so teeth every three to four months,

    牠們每 3 至 4 個月便會換掉所有的牙齒,大約 100 顆左右,

  • and since geckos can live for six to 10 years,

    由於壁虎可以活到 6 至 10 年,

  • they'll grow anywhere from 1,800

    牠們一生可以長 1 千 8 百顆至

  • to 4,000 teeth in a lifetime.

    4 千顆牙齒。

  • That's all thanks to a special type of cell in their gums

    這都要感謝牠們的牙齦裡一種特殊的細胞,

  • called stem cells.

    稱為幹細胞。

  • Stem cells are handy because they can morph into different

    幹細胞非常有用,因為它們可以合成不同細胞,

  • cells when needed,

    尤其在有需要時,

  • like tooth stem cells to build new teeth.

    譬如牙齒幹細胞可以生成新的牙齒。

  • Humans have these stem cells when we're younger,

    人類年輕的時候擁有這些幹細胞,

  • but after our adult teeth grow in,

    但當我們的成年牙齒生長後,

  • the stem cells die and disappear.

    這些幹細胞就會死去消逝。

  • To understand why, let's take a journey back in time

    想要了解原因,讓我們回到過去,

  • to about 320 million years ago when mammals

    大約 3 億 2 千萬年前,當時哺乳類

  • and reptiles split off.

    和爬蟲類分開。

  • In addition to many obvious differences,

    除了許多明顯外貌上的差異,

  • another change that eventually emerged was tooth shape.

    另一個永久差異是牙齒結構。

  • Reptiles, for example, are what's called generalists,

    以爬蟲類來說,又稱廣適者,

  • meaning they eat the animals they can get their teeth on.

    意味牠們可以把吃下肚的動物的牙齒歸於己用,

  • And for that, they needed teeth with the same size and shape

    為此,牠們需要同樣尺寸結構的牙齒,

  • to keep prey from escaping their mouths.

    以防止獵物從牠們的嘴裡逃出。

  • Mammals, on the other hand, developed more specific diets,

    另一方面,哺乳類發展固定的獵食習慣,

  • like grazers who only eat grass and hunters who rip flesh

    譬如食草動物只吃草,獵人只取用獵物

  • from their kills.

    身上的肉。

  • As a result, mammals evolved different-shaped teeth

    因此,哺乳類演化成不同結構的牙齒

  • for different purposes.

    有其不同的目的。

  • And it's this difference that could also explain

    這樣的差異便可以解釋

  • why mammals can't regrow more teeth.

    為何哺乳類不能重新生長更多的牙齒。

  • Now, let's say you could regrow your molars multiple times, for example.

    現在,假設說你的臼齒可以重新生長好幾次。

  • It's important that the top and bottom sets match up.

    上排和下排的牙齒能夠咬合是非常重要的。

  • Otherwise, they can't grind food as efficiently.

    如果不這麼做,就不能正確有效率地咀嚼。

  • That sounds good in principle, but with each new set,

    聽起來好像理論上可行,但是每長一顆新牙,

  • there's a risk that the regrown teeth won't line up.

    這些新牙會有無法排列整齊的風險。

  • So the leading theory is that adult humans can't regrow

    所以研究指出成人無法生長新牙,

  • our teeth because it was better for survival

    是因為如要生存,

  • to only grow one well-aligned adult set.

    只要生長一組排列良好的成人牙齒即可。

  • However, if you still wish you could regrow a tooth,

    然而,如果你還是希望能重新長牙,

  • there may be a way in the future.

    或許未來可行。

  • Using lasers and drugs, scientists have helped rats and mice

    科學家已經透過雷射以及藥物,幫助老鼠

  • regrow damaged tissue in cavity-ridden teeth

    在蛀牙的牙洞中重新修復受損的組織。

  • with the idea that if you could regrow tooth tissue,

    以這樣的做法來說,如果你的牙齒組織可以重新生長,

  • you could eventually regrow entire teeth,

    最終必定也可以長出新的一副牙齒,

  • though no human testing has been done on that yet.

    不過目前這個實驗還沒有做過人類測試就是了。

  • So keep flossing and keep seeing your dentist.

    所以還是繼續用牙線清潔牙齒以及定期看牙醫吧。

  • At least for now.

    至少目前來說是必要的。

- [Narrator] Humans need dentists. It's a fact.

〔旁白〕人類需要牙醫,這是無法抹滅的事實。

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