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  • Hey there and welcome to LifeNoggin.

  • Viruses are one of the earliest forms of life as we know it.

  • They're little strings of genetic material (called RNA) coated in a protein jacket.

  • They've evolved to make people sick in very specific ways.

  • They hijack cells and use the cells to produce more viruses.

  • Once the virus is ready, can force its host to share it with others.

  • For example, the varicella-zoster virus (VZV) causes little red spots to appear all over

  • the infected person.

  • We call them chicken pox!

  • They are

  • VERY.

  • ITCHY, and the virus did that on purpose!

  • It fills the pox with more viruses, so when people scratch them, they let the virus out

  • of their body, spreading it to people nearby.

  • It's actually pretty smart.

  • And this is how lots of viruses move through the population.

  • They get inside a body, and after a few days -- or, sometimes, years -- they'll try and

  • hitch a ride to another body.

  • The time from when they get inside a person to when they try and spread, is called the

  • incubation period.

  • During that time, the virus is invading cells, and fighting the immune system.

  • During the incubation period, if you have a virus, you might not even notice!

  • Chickenpox can take weeks before the first pox appear!

  • The flu, another common virus, is less patient.

  • Its incubation period is only half of a day.

  • It really wants to get out into the world again.

  • The flu spreads so fast through your friends because it can spread so fast in your body

  • too.

  • The influenza virus evolved to make you cough and sneeze, so it can hitch a ride on the

  • tiny droplets of water that come out when you do so!

  • Let's say Ian has the flu and coughs, then Autumn inhales a few droplets (even way later

  • in the day)...

  • Once inside her body, influenza virus hopes to hit an epithelial cell.

  • Epithelial cells line the airway and are the perfect place for a new flu virus to set up

  • shop.

  • Once it finds the right cell, it has to get inside, but cells don't just let anyone off

  • the street inside their membranes.

  • So, to convince the cell to let it in, viruses have little bumps on the outside of their

  • jacket -- called receptors.

  • Receptors are like keys, and if the virus has the right key, our cell will surround

  • it -- called endocytosis.

  • This can happen less than 10 minutes after a flu droplet is inhaled!

  • Once inside the cell, the influenza takes off its jacket -- it transforms.

  • From there, the little bit of genetic RNA material heads to nucleus of the cell, and

  • does something called "cap snatching."

  • It steals a "cap" from the host cell's RNA molecules and puts it on itself.

  • Once it's wearing the cap, the flu virus can trick the DNA in the nucleus to make more

  • flu virus -- again and again and again.

  • As more and more virus fills up the cytoplasm, the new guys steal bits of the cell's outer

  • membrane to put on a jacket and head out into the body.

  • Even though the influenza virus invades human cells really quickly, it can take a day or

  • two before you'll feel sick.

  • The immune system is on the prowl looking for infected cells and any virus in your bloodstream.

  • It's huge battle!

  • If you have a fever, or feel sore and achy, that's a side-effect of your immune system

  • attacking an infection.

  • Fevers change the body's temperature to try and slow the virus down.

  • The achyness comes from our own body try helping the immune cells trying to fight the infection.

  • After a few days, the immune system usually wins out, but chances are you've already spread

  • the virus to someone else.

  • Which means you've won the battle, but lost the war.

  • In the end, viruses aren't trying to hurt us, they're just fighting to survive.

  • They can be annoying, dangerous and even deadly, but learning about how they work has taught

  • us a lot about ourselves, and the history of life on our planet.

  • This video was written by our good friend Trace Dominguez.

  • He's got a YouTube channel where he looks at how the world works through the lens of

  • history and science.

  • Check out his latest series here where he explores the how the television business got

  • so big!

  • Make sure you come back every Monday for a brand new video.

  • As always, I'm Blocko and this has been Life Noggin.

  • Don't forget to keep on thinking!

Hey there and welcome to LifeNoggin.

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