Name: 韋戈維與兒童肥胖症的未來 (Wegovy and the future of childhood obesity)
Uploaded: 2025-07-20T17:31:13.000Z
Duration: 35 min 43 s

程度副詞

So I'm just going to start by having you tell me what your name is.

所以，我先讓你告訴我你叫什麼名字。

Austin Smith is about to start his senior year in a high school just outside of Kansas

奧斯汀-史密斯即將在堪薩斯州外的一所高中開始他的高三生活

And while he's preparing for his final year of school and considering his options for life after graduation, he's doing so with a renewed self-image.

他正在為最後一年的學業做準備，考慮畢業後的人生選擇，同時他也在重新樹立自我形象。

Austin is one of nearly 100,000 young people who've started taking Wagovi and other powerful weight loss drugs to manage chronic obesity.

奧斯汀是近 10 萬名開始服用瓦戈維和其他強效減肥藥物來控制慢性肥胖的年輕人之一。

Eight million teens in the U.S. are living with obesity and with it the increased risk of developing chronic diseases like type 2 diabetes, liver disease, and heart conditions.

美國有 800 萬青少年患有肥胖症，患 2 型糖尿病、肝病和心臟病等慢性疾病的風險也隨之增加。

And faced with the more immediate threat of bullying and social isolation that can cause serious mental health risks.

他們還面臨著更直接的威脅--欺凌和社會孤立，這可能會造成嚴重的心理健康風險。

There's this one kid who called me pregnant because of my weight, which is a main one.

有一個孩子因為我的體重說我懷孕了，這是最主要的原因。

And that's the one, that's the main one that I can remember that stuck through me.

So young people like Austin find themselves at a difficult crossroads.

是以，像奧斯汀這樣的年輕人發現自己正處於一個艱難的十字路口。

Do they continue down a path of conventional treatments like diet and exercise that often yield minimal, if any, weight loss results?

他們是否會繼續採用節食和運動等傳統治療方法，而這些方法的減肥效果往往微乎其微？

Or begin what could be a lifelong treatment using these powerful GLP-1 injections, despite concerns from doctors about nutritional deficiencies, eating disorders, and unknown long-term health effects.

或者開始使用這些強效 GLP-1 注射劑進行可能是終生的治療，儘管醫生們擔心營養不良、飲食紊亂和未知的長期健康影響。

For Austin, his final year of high school is shaping up to look much different than how it began.

對於奧斯汀來說，他高中的最後一年將與開始時大不相同。

Whenever I started walking onto the bus, I noticed that my sides weren't constantly hitting the seats of the bus since they're pretty narrowed together, which made me feel really happy and I was really ecstatic to tell my parents when I got home.

每當我開始走上公車時，我發現我的身體兩側並沒有經常撞到公車的座位上，因為公車的座位非常窄，這讓我感到非常高興，回家後我非常高興地告訴我的父母。

But Austin's journey, like so many others, hasn't come without setbacks and struggles.

但是，奧斯汀的人生旅途和其他許多人一樣，並非沒有挫折和掙扎。

On this special episode of Reuters World News, we'll talk to a parent taking the leap on a new medication that could bring her son much-needed relief from his struggles with weight.

在本期《路透社世界新聞》特別節目中，我們將採訪一位家長，她的兒子正在嘗試一種新的藥物，這種藥物可以緩解他與體重的抗爭。

We hear from health care providers considering how to use this powerful medication facing an epidemic of youth obesity.

面對青少年肥胖症的流行，醫護人員正在考慮如何使用這種強效藥物。

And what the future looks like for those young people hoping this medicine will be the answer.

對於那些希望這種藥物能夠解決問題的年輕人來說，未來會是怎樣？

I'm your host, Christopher Waljasper in Chicago.

我是主持人克里斯托弗-沃爾賈斯帕爾（Christopher Waljasper），我在芝加哥。

When these powerful weight-loss drugs became available to adults back in 2021, they came with a lot of questions.

早在 2021 年，這些強效減肥藥開始在成人中使用時，就伴隨著許多問題。

But when the Food and Drug Administration approved the use of Wagovi for people as young as 12 almost three years ago, the questions shifted.

但是，當美國食品和藥物管理局近三年前準許年僅 12 歲的兒童使用 Wagovi 時，問題就發生了轉變。

No longer was it a conversation between a patient and a doctor.

這不再是病人和醫生之間的對話。

Now parents are having these discussions with their teens about the potential benefits as well as possible repercussions that these medications could have on a young person going through a lot of changes.

現在，家長們正在與青少年討論這些藥物可能帶來的益處，以及對正在經歷巨大變化的青少年可能產生的影響。

Things like hormones, growth spurts, body image, social media.

比如荷爾蒙、生長高峰、身體形象、社交媒體。

So two of our health care reporters, Chad Terhune and Robin Respo, decided to follow a handful of young people and their families to better understand how they're approaching the decision to try these powerful weight-loss drugs.

是以，我們的兩位醫療保健記者 Chad Terhune 和 Robin Respo 決定跟蹤一些年輕人及其家庭，以更好地瞭解他們是如何決定嘗試這些強效減肥藥的。

Chad, Robin, thanks for joining me today.

查德、羅賓，感謝你們參加今天的節目。

So in all these conversations you had with young people and their loved ones, what were the considerations, things that were going through their minds as they decided whether or not to take this medication?

那麼，在你與年輕人及其親人的談話中，他們在決定是否服用這種藥物時，有哪些考慮因素和想法？

So when we started reaching out to families, a lot of the families were considering, one, whether they could access these medicines because health insurance was still very limited and still for many people is today.

是以，當我們開始接觸這些家庭時，很多家庭都在考慮，第一，他們能否獲得這些藥物，因為當時的醫療保險仍然非常有限，而且對很多人來說，今天仍然如此。

And almost all families we spoke to did not want their children on the drug for the long term or a lifetime.

幾乎所有與我們交談過的家庭都不希望自己的孩子長期或終生服用這種藥物。

And for the kids, they had different priorities.

對孩子們來說，他們有不同的優先事項。

We spoke with doctors and parents who wanted their kids to be healthy.

我們採訪了醫生和家長，他們都希望自己的孩子身體健康。

And in some cases, that was the case for the kids as well.

在某些情況下，孩子們也是如此。

But for other kids, they wanted bullying or negative attention that they had received.

但對於其他孩子來說，他們想要的是自己受到的欺凌或負面關注。

They felt in part because of their weight to stop and they felt like the drugs would help stop the bullying.

他們覺得部分原因是自己的體重，他們覺得藥物可以幫助他們停止欺凌。

Chad, of the medical experts you all spoke to, how are they approaching this medication as a possible tool in combating obesity among young people?

查德，在與你們交談過的醫學專家中，他們是如何看待這種藥物作為防治青少年肥胖症的一種可能工具的？

Yeah, I think a lot of pediatricians we talked to who are really alarmed at the rate of disease in young people.

是的，我想我們接觸過的很多兒科醫生都對年輕人的患病率感到震驚。

Many pediatricians never would have seen a child with type 2 diabetes for much of their career.

許多兒科醫生在其職業生涯的大部分時間裡從未見過 2 型糖尿病患兒。

And now it was becoming increasingly common to have 14-year-olds, 15-year-olds diagnosed with type 2 diabetes.

現在，14 歲、15 歲的孩子被診斷出患有 2 型糖尿病的情況越來越普遍。

And then what they told us was the disease accelerated so much faster in these young people.

然後他們告訴我們，這些年輕人的病情發展得更快。

The complications were coming so much faster.

And so you have people in their early 20s really facing some dire health circumstances.

是以，20 歲出頭的年輕人確實面臨著嚴峻的健康狀況。

And then you also had liver disease and possibly heart disease.

你還患有肝病，可能還有心臟病。

And so you start to have this effect where you could have people in their 30s and 40s possibly dying from preventable diseases.

是以，你就會開始產生這樣的影響：三四十歲的人可能死於可預防的疾病。

The recommendation up until now has been this intensive lifestyle counseling program.

到目前為止，我們一直建議採用這種強化的生活方式諮詢方案。

And oftentimes it was a huge time commitment.

很多時候，這需要投入大量的時間。

And the results, frankly, were often lackluster.

坦率地說，結果往往乏善可陳。

So I think when these medications came on, there was a huge relief of like, wow, we have something we can offer these families that would be much easier to access and maybe would be even more effective.

是以，我認為，當這些藥物出現時，大家都鬆了一口氣，覺得哇，我們可以為這些家庭提供一些更容易獲得的東西，也許會更有效。

And so I think pediatricians and a lot of obesity specialists were very open to this.

是以，我認為兒科醫生和許多肥胖症專家對此持非常開放的態度。

But then you certainly had a lot of other experts saying, oh, my gosh, what are we doing?

不過，肯定也有很多其他專家說，天哪，我們在做什麼？

Because adults are one thing, adolescents, that is a critical phase of development.

因為成年人是一回事，青少年則是發展的關鍵階段。

It just, if you think of your cognitive development, your brain, your bone health, as a teen, you need to be consuming a lot of calories because that is just feeding all of this development in your body.

如果你考慮到你的認知發展、你的大腦、你的骨骼健康，作為一個青少年，你需要攝入大量的卡路里，因為這只是在餵養你身體的所有這些發展。

And so I think there was just a concern of like, sure, there's some immediate payoff.

是以，我認為，人們只是擔心，當然，會有一些立竿見影的效果。

Maybe we prevent type two diabetes, heart disease, sleep apnea, a bunch of really troubling things.

也許我們可以預防二型糖尿病、心臟病、睡眠呼吸暫停等一系列令人頭疼的疾病。

但從長遠來看，我們對他們做了什麼？

And there was really no science or clinical trials that told us long term what's going to happen with these kids five, 10 years down the road.

從長遠來看，沒有任何科學或臨床試驗能告訴我們這些孩子在五年或十年後會發生什麼。

Do we have a clear understanding of why we've seen a rise in obesity and some of these more troubling health concerns in younger people?

我們是否清楚地瞭解為什麼肥胖症和一些更令人擔憂的健康問題會在年輕人中出現？

I think obesity is a very complicated disease and it is a chronic disease and a mix of factors

我認為肥胖症是一種非常複雜的疾病，它是一種慢性病，是多種因素的混合體。

I think drive it, and everybody's different.

我覺得開車，每個人都不一樣。

Certainly your genetics can play a role, certainly the environment we live in.

當然，遺傳因素和我們所處的環境也有一定的關係。

But like, yeah, if you look at the statistics, I mean, back in 1980, it was only about 5% of children or teens had obesity, and now it's more than 20%.

但是，是的，如果你看看統計數據，我的意思是，早在1980年，只有大約5%的兒童或青少年患有肥胖症，而現在已經超過了20%。

So something's certainly changed, and I think it was a whole range of factors.

是以，肯定有什麼東西發生了變化，我認為這是一系列因素造成的。

But I think for a lot of these families and these teens to finally go into a doctor's office and not be blamed, not to face that stigma, and so many of them live that time and time again, a doctor basically talking down to them and really casting blame on them.

但我認為，對於很多家庭和青少年來說，他們終於可以走進醫生的辦公室，而不是被指責，不是面對這種恥辱，他們中的很多人一次又一次地生活在這種情況下，醫生基本上是在對他們說三道四，真的是在指責他們。

And certainly I think the parents felt a lot of guilt, like this is my fault.

當然，我認為家長們會感到非常內疚，覺得這是我的錯。

There are whole factors that lead to this, and it's not because you're a bad parent.

導致這種情況的因素有很多，但這並不是因為你是個不稱職的家長。

It's not because you didn't have enough willpower to say no.

這不是因為你沒有足夠的意志力去拒絕。

This is a disease just like type 2 diabetes and a whole range of things.

這是一種疾病，就像 2 型糖尿病和其他一系列疾病一樣。

And I think finally, they reach some doctors who are like, you know what, we're going to work on this together.

我想最後，他們終於接觸到了一些醫生，他們會說，你知道嗎，我們要一起解決這個問題。

You don't need to be carrying all this shame and stigma.

你不需要揹負這些恥辱和汙名。

So I think that's the other part of this story.

是以，我認為這就是故事的另一部分。

And I think the medical establishment has had to come to grips with, we didn't always talk about this in the right way.

我認為，醫療機構必須認識到，我們並不總是以正確的方式談論這個問題。

And with some of the families we spoke to, there was a strong family history of obesity, which is indicative of a potential genetic cause.

在與我們交談過的一些家庭中，肥胖症的家族史很強，這表明可能存在遺傳原因。

Another teen had a brain tumor when she was younger that had damaged part of her brain that influenced her metabolism.

另一位青少年在年輕時患過腦瘤，腦瘤損傷了她大腦的一部分，影響了她的新陳代謝。

And another girl had PCOS or polycystic ovary syndrome, which increases the risk of weight gain.

還有一個女孩患有多囊卵巢綜合症，這會增加體重增加的風險。

So it was a wide variety of potential reasons.

是以，潛在的原因是多方面的。

And again, as Chad said, obesity is a complex disease, and we still don't really know what causes it.

同樣，正如查德所說，肥胖症是一種複雜的疾病，我們仍然不知道它的病因是什麼。

But there seems to be risk factors, and many of these children had one or more of those risk factors.

但似乎存在一些風險因素，而這些兒童中的許多人都有一個或多個風險因素。

Next, we'll talk to a parent who's faced this decision about how to best help a child struggling with their weight and considered these new powerful weight loss drugs.

接下來，我們將採訪一位家長，他也曾面臨過如何更好地幫助與體重作鬥爭的孩子的決定，並考慮過這些新型強效減肥藥物。

To better understand how these families are approaching these decisions, we wanted to talk to a parent who's been there.

為了更好地瞭解這些家庭是如何做出這些決定的，我們想採訪一位親身經歷過的家長。

So Chad and Robin connected me with Elizabeth Smith.

於是，查德和羅賓幫我聯繫了伊麗莎白-史密斯。

She's the mother of Austin, who we heard from earlier.

她是奧斯汀的母親，我們之前聽過奧斯汀的故事。

伊麗莎白，感謝你參加今天的節目。

We also reached out to Dr. Elena Vidmar, an associate professor of pediatric endocrinology and the medical director of the Obesity Medicine and Bariatric Surgery Program at Children's

我們還聯繫了兒童醫院兒科內分泌學副教授兼肥胖醫學和減肥手術項目醫療主任 Elena Vidmar 博士。

OK, so Elizabeth, give us a sense of who your son Austin is.

好的，那麼伊麗莎白，給我們介紹一下你的兒子奧斯汀吧。

字幕列表影片播放

韋戈維與兒童肥胖症的未來 (Wegovy and the future of childhood obesity)

chronic

stick

potential

struggle