Itturnsoutmanybacteria, buteveninyourcell, someofthe D N A strandsareactuallycloseloops, andsomeofthemareactuallyhappentobe.
Notthatifyouhavesoveryclose D n a strandthatmaybenotthat, andyoucanseeinthiscasetheremaybe a particulargroupexposed, anditcanundergosomechemicalinteractionwithothermolecules.