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  • For centuries, humans have been using substances to alter their state of mind.

    幾世紀以來,人類一直使用物質改變精神狀態。

  • From caffeine, cigarettes and alcohol, to more extreme drugs.

    從咖啡、香菸、酒精,到毒品。

  • But as the most commonly used illicit drug in North America, where does marijuana fit in?

    但在北美洲最普遍使用的非法毒品大麻,又是怎樣呢?

  • And how exactly does it effect your brain?

    大麻對腦部的影響有哪些?

  • First, we need to understand how the brain functions.

    首先,我們必須先了解大腦的機制。

  • Your neurons are the cells that process information in the brain,

    神經細胞會把訊息傳導到腦部。

  • by releasing chemicals called "neuro-transmitters" from the axon of one neuron to the dendrite of another.

    大腦藉由釋放「神經傳導物質」將訊息從一個神經元軸突傳送到另一個。

  • They change the electrical charge of the receiving neuron, consequently exciting or inhibiting it.

    神經傳導物質會改變接收神經元的電荷,並激活或抑制它們。

  • If excited, the signal is passed on.

    如果激活了,信息將被傳送。

  • Though it sounds simple, these signals work together and the effect is quickly compounded into complex configurations within milliseconds, flushing over the entire brain.

    雖然這聽起來很簡單,但這些訊號彼此合作,在幾毫秒內迅速配製複雜的結構達到效果,並傳遍整個大腦。

  • This is what happens every single time you think, breath, or move.

    這就是每當你思考、呼吸或移動時腦部運作的情況。

  • So what is going on inside your brain when you are smoking marijuana?

    那當你吸大麻時,腦部會如何運作呢?

  • Well, unlike alcohol which contains molecules nothing like those in our body.

    不像酒精分子與人體分子完全不同,可被排出體外。

  • Cannabis contains molecules that resemble those produced in our very own brains.

    大麻分子與我們腦部分子十分相似。

  • Cannabinoids, though naturally these cannabinoids circulate in much lower quantities compared to the large influx imposed by smoking.

    體內的自然微量大麻素比由抽大麻造成的量來得少得多。

  • Specifically the chemical Tetrahydrocannabinol, or THC, resembles a natural transmitter called Anandamide.

    特別是化學物質「四氫大麻酚」,簡稱 THC。它與一種天然傳導物質「阿南達胺」很相似。

  • These cannabinoids are specialized neurotransmitters released by neurons having just fired.

    大麻素就是神經元發射後所產生的特殊神經傳遞素。

  • Neurons temporarily becomes unresponsive after firing, to prevent them from overreacting or being to dominant.

    原本神經元發射後會暫時失效,可防止它們反應過度或過度活躍。

  • This allows your brain to function in a calm and controlled manner.

    這使你的大腦得以冷靜及受控的運作。

  • But cannabinoids interrupt this approach in some parts of the brain.

    但大麻素會擾亂腦中這方面的運作。

  • Instead, they remove the refractory period of neurons, that are already active and cause your thoughts, imagination and perception to utterly magnify itself.

    大麻素會去除掉原本神經元的不反應期,並加強放大你的幻想與知覺。

  • This means once you begin your train of thought, it becomes the most significant and profound thing ever.

    這意味著當你開始思考,任何事都會變得非常顯著且深刻。

  • You can't see the big picture or even recall your last epiphany, because you are caught up in the momentum of a particular idea, and your neurons keep firing.

    你看不到事情的全面,也沒有任何一絲記憶,只能想著特定一件事,神經元也會持續活躍。

  • Until a new idea takes hold, and you go off on a new tangent.

    直到新的想法闖入,你的思考才切到新的路線。

  • These cannabinoids also effect the levels of dopamine and norephinephrine in your brain.

    大麻素也會影響大腦中多巴胺與正腎上腺素的量。

  • Often leading to a sense of euphoria, relaxation, pain modulation and general enhancement of an experience, though sometimes causing anxiety.

    這通常會造成興奮、肌肉鬆弛,並增強疼痛調節和感知,但有時也會引起焦慮。

  • Furthermore, there are cannabinoid receptors in areas controlling short term memory, learning, coordination, movement control and higher cognitive functions.

    此外,有些大麻素也存在於某些控制短期記憶、學習、協調、運動控制和高級認知功能的區域。

  • Got a burning question you want answered? Ask it in the comments or on facebook and twitter.

    有迫切想知道答案的問題嗎?於留言區或前往 Facebook 和 Twitter 留言吧!

  • And subscribe for more weekly science videos.

    別忘記訂閱收看每週最新科學影片。

For centuries, humans have been using substances to alter their state of mind.

幾世紀以來,人類一直使用物質改變精神狀態。

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