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One way to change our genes is to make new ones,
譯者: Bill Hsiung 審譯者: Mandy Lo
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as Craig Venter has so elegantly shown.
改變我們基因的方法之一,是製造新的基因,
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Another is to change our lifestyles.
如同克萊格•凡特之前優雅的演說一般。
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And what we're learning is how powerful and dynamic these changes can be,
另一個方法是,改變我們的生活作息。
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that you don't have to wait very long to see the benefits.
我們所學到的是,這些改變可以非常迅速與有效,
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When you eat healthier, manage stress, exercise and love more,
你不需要等待太久,就能察覺它的效益。
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your brain actually gets more blood flow and more oxygen.
當你吃得更健康,有效紓解壓力,運動與保持喜樂,
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But more than that, your brain gets measurably bigger.
你腦部血液循環會增加,因而獲得更多氧氣。
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Things that were thought impossible just a few years ago
除此之外,你的腦容積會明顯地變大。
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can actually be measured now.
幾年前被認為不可能的事,
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This was figured out by Robin Williams
而現在能被測知了。
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a few years before the rest of us.
這一點羅賓•威廉斯
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Now, there's some things that you can do
比我們還要更早幾年知道。(電影:窈窕奶爸)
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to make your brain grow new brain cells.
因此,你可以做一些事情來
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Some of my favorite things, like chocolate and tea, blueberries,
促使你的腦增生新的腦細胞。
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alcohol in moderation, stress management
一些我最喜愛的事物,像是巧克力、茶、藍莓、
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and cannabinoids found in marijuana.
適度的飲酒,良好的情緒管理
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I'm just the messenger.
還有大麻中的大麻醇。
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(Laughter)
我只是傳遞訊息而已。
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What were we just talking about?
(全場大笑)
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(Laughter)
我們剛剛談到哪裡?
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And other things that can make it worse,
(全場大笑)
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that can cause you to lose brain cells.
其他這些事情可以使情形惡化,
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The usual suspects, like saturated fat and sugar,
它們可以讓你失去腦細胞。
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nicotine, opiates, cocaine, too much alcohol and chronic stress.
它們是我們常聽到的,像是:飽和脂肪與糖類、
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Your skin gets more blood flow when you change your lifestyle,
尼古丁、嗎啡、古柯鹼、過量飲酒與慢性的壓力。
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so you age less quickly. Your skin doesn't wrinkle as much.
當你改變生活作息的同時,皮膚的血液循環也會增加,
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Your heart gets more blood flow.
因此可以減緩老化,減少皺紋產生。
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We've shown that you can actually reverse heart disease.
你的心臟獲得更多的血液供給。
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That these clogged arteries that you see on the upper left,
我們已經證明,你可以逆轉心臟疾病的生成。
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after only a year become measurably less clogged.
你們在左上圖所看到的這些動脈阻塞,
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And the cardiac PET scan shown on the lower left,
在短短的一年後變得暢通許多。
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the blue means no blood flow.
而在左下圖是心血管正子掃描結果,
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A year later -- orange and white is maximum blood flow.
藍色意味著沒有血液流過。
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We've shown you may be able to stop and reverse the progression
一年後 — 橘色和白色表示血液循環非常暢通。
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of early prostate cancer and, by extension, breast cancer,
我們已經證明,你可以停止或是反轉
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simply by making these changes.
早期攝護腺癌(另譯:前列腺癌)的發生,推測乳癌也適用,
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We've found that tumor growth in vitro was inhibited
只要做出這些改變。
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70 percent in the group that made these changes,
當病人作出這些改變,
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whereas only nine percent in the comparison group.
他們的癌細胞在試管培養實驗發現生長力降低了 70%,
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These differences were highly significant.
而對照組只降低了 9%。
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Even your sexual organs get more blood flow,
這些差異非常的顯著。
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so you increase sexual potency.
甚至你性器官的血液循環也會增加,
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One of the most effective anti-smoking ads was done
所以你的性能力會跟著增加。
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by the Department of Health Services,
衛生局製作出了最有效的
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showing that nicotine, which constricts your arteries,
反菸害廣告之一,
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can cause a heart attack or a stroke,
告訴人們,尼古丁會使動脈收縮,
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but it also causes impotence.
導致心臟病發作或是中風,
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Half of guys who smoke are impotent.
同時也會引發性無能。
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How sexy is that?
半數吸煙的男士有性功能障礙。
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Now we're also about to publish a study --
這樣能多性感?
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the first study showing you can change gene expression in men with prostate cancer.
我們也即將發表一則研究 —
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This is what's called a heat map --
這個研究顯示,你可以改變攝護腺癌男士的基因表現。
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and the different colors -- and along the side, on the right, are different genes.
這是我們稱之為基因熱圖的資料。
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And we found that over 500 genes were favorably changed --
這些不同的顏色,在投影片右邊你可以看到,表示不同的基因。
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in effect, turning on the good genes, the disease-preventing genes,
我們發現,超過五百個基因呈現好轉趨勢,
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turning off the disease-promoting genes.
開啟好的基因,能防止疾病的基因,
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And so these findings I think are really very powerful,
關閉會促使疾病產生的基因。
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giving many people new hope and new choices.
我認為,這些發現是非常有用的。
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And companies like Navigenics and DNA Direct and 23andMe,
能為許多人帶來新的希望與選擇。
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that are giving you your genetic profiles,
而那些像是 Navigenix, DNA Direct 和 23andMe 等
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are giving some people a sense of, "Gosh, well, what can I do about it?"
提供你個人基因資訊的公司,
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Well, our genes are not our fate, and if we make these changes --
會為某些人帶來命定論的感覺,「老天,我能怎麼辦?」
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they're a predisposition -- but if we make bigger changes
這麼嘛,我們的基因不能決定我們的命運,只要我們能做改變 —
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than we might have made otherwise,
它們是你的體質傾向,但如果我們做出更大的改變,
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we can actually change how our genes are expressed.
我們可以改變它的方向,
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Thank you.
我們可以改變我的的基因如何表現。
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(Applause)
謝謝大家。